2', 3'-Dideoxyinosine has been approved as an anti-HIV drug. Propose a mechanism by which it might block the growth of the HIV virus. Match the words in the left column to the appropriate blanks in the sentences on the right. dideoxynucleoside 3' triphosphate dideoxynucleoside 5' phosphate + endonuclease dATP 5' phosphate terminus dGTP dideoxynucleoside 3' phosphate Dideoxyinosine (ddl) is taken up into the cell and converted to the corresponding Incorporation of this nucleotide in place of because of the absence of a Reset Help it incorporates replication of the viral genome to be selectively inhibited. would block further chain elongation The HIV reverse transcriptase lacks a more readily than do the cellular replicative polymerases, causing SO

Biology: The Unity and Diversity of Life (MindTap Course List)
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Chapter8: Dna Structure And Function
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Problem 3DAA: HersheyChase Experiments The graph shown in FIGURE 8.5 is reproduced from an original 1952...
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2', 3'-Dideoxyinosine has been approved as an anti-HIV drug. Propose a mechanism by which it might block the growth of the HIV virus.
Match the words in the left column to the appropriate blanks in the sentences on the right.
dideoxynucleoside 3'
triphosphate
dideoxynucleoside 5'
phosphate
endonuclease
dATP
5' phosphate terminus
dGTP
dideoxynucleoside 3'
phosphate
3'-exonuclease
dideoxynucleoside 5'
triphosphate
3' hydroxyl terminus
5'-exonuclease
dTTP
Dideoxyinosine (ddI) is taken up into the cell and converted to the corresponding
Incorporation of this nucleotide in place of
because of the absence of a
it incorporates
replication of the viral genome to be selectively inhibited.
Reset Help
would block further chain elongation
The HIV reverse transcriptase lacks a
more readily than do the cellular replicative polymerases, causing
SO
Transcribed Image Text:2', 3'-Dideoxyinosine has been approved as an anti-HIV drug. Propose a mechanism by which it might block the growth of the HIV virus. Match the words in the left column to the appropriate blanks in the sentences on the right. dideoxynucleoside 3' triphosphate dideoxynucleoside 5' phosphate endonuclease dATP 5' phosphate terminus dGTP dideoxynucleoside 3' phosphate 3'-exonuclease dideoxynucleoside 5' triphosphate 3' hydroxyl terminus 5'-exonuclease dTTP Dideoxyinosine (ddI) is taken up into the cell and converted to the corresponding Incorporation of this nucleotide in place of because of the absence of a it incorporates replication of the viral genome to be selectively inhibited. Reset Help would block further chain elongation The HIV reverse transcriptase lacks a more readily than do the cellular replicative polymerases, causing SO
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