2. Aspirin is absorbed into the blood through the cells lining the stomach and the small intestine. Absorption requires passage through the plasma membrane, the rate of which is determined by the polarity of the molecule: charged and extremely polar molecules pass slowly, whereas neutral and hydrophobic ones pass rapidly a. The pH inside the stomach is around 2.0 and the pH of the contents of the small intestine is about 6.0. Which of the following statements is correct: i. The small intestine has 3 times lower [H] than the stomach. ii. The small intestine has 4 times lower [H ] than the stomach iii. The small intestine has 3,000 times lower [H] than the stomach iv. The small intestine has 10,000 times lower [H] than the stomach. b. The pKa of aspirin is 3.5. Draw the predominant form of aspirin and its overall charge (-1,0 or +1) when it is in the stomach or in the small intestine: Small Intestine (pH= 6.0): Stomach (pH 2.0) Overall Charge: Overall Charge:

Principles of Modern Chemistry
8th Edition
ISBN:9781305079113
Author:David W. Oxtoby, H. Pat Gillis, Laurie J. Butler
Publisher:David W. Oxtoby, H. Pat Gillis, Laurie J. Butler
Chapter15: Acid–base Equilibria
Section: Chapter Questions
Problem 58P
icon
Related questions
Question
2. Aspirin is absorbed into the blood through the cells lining the stomach and the small intestine. Absorption
requires passage through the plasma membrane, the rate of which is determined by the polarity of the molecule:
charged and extremely polar molecules pass slowly, whereas neutral and hydrophobic
ones pass rapidly
a. The pH inside the stomach is around 2.0 and the pH of the contents of the small intestine is about 6.0.
Which of the following statements is correct:
i. The small intestine has 3 times lower [H] than the stomach.
ii. The small intestine has 4 times lower [H ] than the stomach
iii. The small intestine has 3,000 times lower [H] than the stomach
iv. The small intestine has 10,000 times lower [H] than the stomach.
b. The pKa of aspirin is 3.5. Draw the predominant form of aspirin and its overall charge (-1,0 or +1) when it
is in the stomach or in the small intestine:
Small Intestine (pH= 6.0):
Stomach (pH 2.0)
Overall Charge:
Overall Charge:
Transcribed Image Text:2. Aspirin is absorbed into the blood through the cells lining the stomach and the small intestine. Absorption requires passage through the plasma membrane, the rate of which is determined by the polarity of the molecule: charged and extremely polar molecules pass slowly, whereas neutral and hydrophobic ones pass rapidly a. The pH inside the stomach is around 2.0 and the pH of the contents of the small intestine is about 6.0. Which of the following statements is correct: i. The small intestine has 3 times lower [H] than the stomach. ii. The small intestine has 4 times lower [H ] than the stomach iii. The small intestine has 3,000 times lower [H] than the stomach iv. The small intestine has 10,000 times lower [H] than the stomach. b. The pKa of aspirin is 3.5. Draw the predominant form of aspirin and its overall charge (-1,0 or +1) when it is in the stomach or in the small intestine: Small Intestine (pH= 6.0): Stomach (pH 2.0) Overall Charge: Overall Charge:
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 6 steps with 4 images

Blurred answer
Similar questions
Recommended textbooks for you
Principles of Modern Chemistry
Principles of Modern Chemistry
Chemistry
ISBN:
9781305079113
Author:
David W. Oxtoby, H. Pat Gillis, Laurie J. Butler
Publisher:
Cengage Learning
Chemistry: The Molecular Science
Chemistry: The Molecular Science
Chemistry
ISBN:
9781285199047
Author:
John W. Moore, Conrad L. Stanitski
Publisher:
Cengage Learning
Chemistry: Principles and Practice
Chemistry: Principles and Practice
Chemistry
ISBN:
9780534420123
Author:
Daniel L. Reger, Scott R. Goode, David W. Ball, Edward Mercer
Publisher:
Cengage Learning
Chemistry
Chemistry
Chemistry
ISBN:
9781133611097
Author:
Steven S. Zumdahl
Publisher:
Cengage Learning
Chemistry
Chemistry
Chemistry
ISBN:
9781305957404
Author:
Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:
Cengage Learning
Chemistry: An Atoms First Approach
Chemistry: An Atoms First Approach
Chemistry
ISBN:
9781305079243
Author:
Steven S. Zumdahl, Susan A. Zumdahl
Publisher:
Cengage Learning