2. (for multiple choice questions circle the correct answer(s)). (a) Provide the necessary reactants that would allow for the efficient formation of the ether below by an SN2 Williamson ether synthesis? CH; CH CH3 (b) What reagent would best accomplish the following reaction? CH2CH2OH CH,CH,Br ? (i) Br2 (ii) NaBr (iii) CH3BR (iv) NH4 Br (v) PB33
Reactions of Ethers
Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.
Epoxides
Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.
Williamson Ether Synthesis
An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.
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