Provide an answer for each in the space provided. 1. Provide a structure for the major product of each reaction. Be sure to include relative stereochemistry if it is pertinent CH3 1. TSCI, EtN 2. NaOCH3 DMF, 100 °C H3C 'CH3 он H2 (1 atm) cat. [Pd] H.
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- For butenafine, develop a synthesis that starts with napthalene and benzene. (aromatic methyl groups can be converted to alkyl bromides using Br2/light, and aldehydes by heating the alkyl bromide in DMSO, eg. ArCH3 to ArCH2Br then to ArCHO).I need specific description of the compounds involved in the synthesis (functional groups, specific features). and also describe the steps involved in the synthesis and the role of each step. And most important!!devote one to each step of the synthesis. Each step should clearly indicate the reagent used, the stereochemistry involved in the reaction and its importance or relevance to the multistep synthesisPlease complete reactions in clear handwritten of all subparts
- Supply the missing reagent in the following reaction: (see attachment) A. Lindlar, H2, mCPBA B. O3 or KMnO4 C. fused KOH D. NH3 E. NaNH2give the reagents for parts a-pProduct C is the thermodynamic product while product B is the kinetic. Define these terms. Construct an energy profile diagram to illustrate your answer with respect to the formation of compounds C and D from A and CH3–Br. Thank you :)
- Provide a retrosynthesis (with complete reaction conditions) of the followingcompound from alkyl halides containing 6 carbons or less. The starting materials may be any type of alkyl halide (primary, secondary, or tertiary). You may use any other reagents you find necessary.(a) Give the names of reagents and conditions for each of the reactions I and IIHello. Kindly help me understand if this is a possible schematic of the reaction. The specific question is in Organic Chemistry Principles and Mechanisms by Joel Karty 2nd Edition, Problem 12.11 on page 614. I believe the predicted major product should come as well as with its enantiomer hence 4 products predicted for this reaction as there is no easy rotation about the cyclic structure
- Complete the following reactions with the majority products and the missing reaction conditions. Indicate stereochemistry if applicable. Also indicate the type of reaction that took place (SN1, SN2, E1, E2, E1bc)In parts 1 and 2 draw the two organic products of this reaction, showing any nonzero formal charges. Then, in part 3 answer the question regarding purification of the reaction mixture. 1. Draw the product with the higher molecular weight here: 2. Draw the product with the lower molecular weight here:Based on your answer to parts A - C, draw the correct regio- and stereoisomer of the product in the space provided. Provide a systematic name of the substrate. Provide a systematic name of the product (see section 8.3 for alkene nomenclature). Draw a transition state structure of the reaction with partial bonds and partial charges indicated. Draw an energy diagram for the E2 reaction on the previous page. Your reaction coordinate diagram should: Include structures of starting materials, products, and transition states at correct relative energies. Indicate the activation energy of the rate determining step and whether the reaction is endothermic or exothermic.