2. Imagine you are a chemist working for a pharmaceutical company, with the task of synthesizıng Valproate, an anti-seizure medication, starting from 2-propyl-1-butene. There are a few ways to perform this overall transformation, but your task is to provide two reactions and the intermediate structure that result in Valproate. Please be sure that your intermediate structure contains any required stereochemistry, lone pairs, and/or formal charges. Y 国 LIAIHY or PCC H30 or H3 0 HO Valproate Anti-Seizure Medication Reaction 1 Intermediate Reaction 2

2. Imagine you are a chemist working for a pharmaceutical company, with the task of synthesizıng Valproate, an anti-seizure medication, starting from 2-propyl-1-butene. There are a few ways to perform this overall transformation, but your task is to provide two reactions and the intermediate structure that result in Valproate. Please be sure that your intermediate structure contains any required stereochemistry, lone pairs, and/or formal charges. Y 国 LIAIHY or PCC H30 or H3 0 HO Valproate Anti-Seizure Medication Reaction 1 Intermediate Reaction 2

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter20: Dienes, Conjugated Systems, And Pericyclic Reactions

Section20.6: Sigmatropic Shifts

Problem 20.12P

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