2. Indicate, using the genetic code, the sequences of amino acids of a part of tyrosinase coded by each of the 2 alleles. 3. Explain how the modification of the nucleotide sequence of an allele leads to the appearance of albinism.

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Chapter1: A View Of Life
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Exercise 1:
Albinism is a hereditary deficiency characterized by the absence of pigmentation in the skin, eyes, and hair,
due to the absence of a black pigment: the melanin.
Tyrosinase is an enzyme implicated in the biosynthesis of this pigment. The gene coding for tyrosinase
exists in different alleles. We consider only 2 alleles: allele A coding for the active tyrosinase responsible for
the synthesis of melanin, and allele B coding for the inactive tyrosinase which doesn't allow the synthesis of
Albinism
melanin.
The document below represents a partial sequence of a strand of the 2 alleles A and B.
Number
80
81
82
83
84
85
of triplet
Allele A
TGC
САА
CGA
ТСС
ТАТ
СТТ
...
Allele B
TGC
САА
САА
TCC
ТАТ
СТТ
...
Transcribed Image Text:Exercise 1: Albinism is a hereditary deficiency characterized by the absence of pigmentation in the skin, eyes, and hair, due to the absence of a black pigment: the melanin. Tyrosinase is an enzyme implicated in the biosynthesis of this pigment. The gene coding for tyrosinase exists in different alleles. We consider only 2 alleles: allele A coding for the active tyrosinase responsible for the synthesis of melanin, and allele B coding for the inactive tyrosinase which doesn't allow the synthesis of Albinism melanin. The document below represents a partial sequence of a strand of the 2 alleles A and B. Number 80 81 82 83 84 85 of triplet Allele A TGC САА CGA ТСС ТАТ СТТ ... Allele B TGC САА САА TCC ТАТ СТТ ...
2. Indicate, using the genetic code, the sequences of amino acids of a part of tyrosinase coded by
each of the 2 alleles.
3. Explain how the modification of the nucleotide sequence of an allele leads to the appearance of
albinism.
Transcribed Image Text:2. Indicate, using the genetic code, the sequences of amino acids of a part of tyrosinase coded by each of the 2 alleles. 3. Explain how the modification of the nucleotide sequence of an allele leads to the appearance of albinism.
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