2. The following pyrrole derivative is a drug under development for schizophrenia and it is prepared by Knorr synthesis. Identify the structure of the two starting materials (ketone and a-aminoketone) required for the synthesis. CH3 H3C, N. CH3 Also, assign the absolute stereochemistry to the chiral centres contained in this drug.
2. The following pyrrole derivative is a drug under development for schizophrenia and it is prepared by Knorr synthesis. Identify the structure of the two starting materials (ketone and a-aminoketone) required for the synthesis. CH3 H3C, N. CH3 Also, assign the absolute stereochemistry to the chiral centres contained in this drug.
Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter23: Amines
Section: Chapter Questions
Problem 23.60P: Following is a retrosynthesis for the coronary vasodilator ganglefene. (a) Propose a synthesis for...
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