Patients with a form of early-onset diabetes were found to carry a variety of mutations reducing the function of theglucokinase (GK) enzyme. These patients are heterozygous for one of the mutations, and thus show only partialrather than complete loss of GK activity. Answer the following questions about these patients.How would blood sugar lovolc likoly bo affoctod in CK nautatie 2. Which of the following is true about normal GK?a. It is an isozyme of hexokinaseb. It requires magnesium as a cofactorIt catalyzes a far from equilibrium reactiond. It functions in the energy investment phase of glycolysisC.e. More than one of these statements is true about normal GKf. All of these statements are true about normal GK

Glucokinase(GK) occurs in the liver and pancreatic cells. Mutation in the gene of GK causes a form…

2. Which of the following is true about normal GK? a. It is an isozyme of hexokinase b. It requires magnesium as a cofactor C. It catalyzes a far from equilibrium reaction d. It functions in the energy investment phase of glycolysis С. е. More than one of these statements is true about normal GK f. All of these statements are true about normal GK

2. Which of the following is true about normal GK? a. It is an isozyme of hexokinase b. It requires magnesium as a cofactor C. It catalyzes a far from equilibrium reaction d. It functions in the energy investment phase of glycolysis С. е. More than one of these statements is true about normal GK f. All of these statements are true about normal GK

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter18: Glycolysis

Section: Chapter Questions

Problem 20P: Understanding the Mechanism of Hemolytic Anemia Genetic defects in glycolytic enzymes can have...

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