21p 21g 1. You performed SNP microaray genotyping on a child diagnosed with Down syndrome and his parents. Only the markers close to the centromere of chromosome 21 are shown. What can you conclude from these data? A. Father т a. Nondisjunction occurred in the father during meiosis 1 b. Nondisjunction occurred in the father during meiosis 2 c. Nondisjunction occurred in the mother during meiosis 1 d. Nondisjunction occurred in the mother during meiosis 2 e. The child does not have trisomy 21. A. Mother Child 2. What does the Philadelphia chromosome refer to?

Human Heredity: Principles and Issues (MindTap Course List)
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Chapter6: Cytogenetics: Karyotypes And Chromosome Aberrations
Section: Chapter Questions
Problem 3QP: A colleague e-mails you saying that she has identified an interesting chromosome variation at 21q13....
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21p
21g
1. You performed SNP microaray genotyping on a child
diagnosed with Down syndrome and his parents. Only the
markers close to the centromere of chromosome 21 are
shown. What can you conclude from these data?
A.
Father
т
a. Nondisjunction occurred in the father during meiosis 1
b. Nondisjunction occurred in the father during meiosis 2
c. Nondisjunction occurred in the mother during meiosis 1
d. Nondisjunction occurred in the mother during meiosis 2
e. The child does not have trisomy 21.
A.
Mother
Child
2. What does the Philadelphia chromosome refer to?
Transcribed Image Text:21p 21g 1. You performed SNP microaray genotyping on a child diagnosed with Down syndrome and his parents. Only the markers close to the centromere of chromosome 21 are shown. What can you conclude from these data? A. Father т a. Nondisjunction occurred in the father during meiosis 1 b. Nondisjunction occurred in the father during meiosis 2 c. Nondisjunction occurred in the mother during meiosis 1 d. Nondisjunction occurred in the mother during meiosis 2 e. The child does not have trisomy 21. A. Mother Child 2. What does the Philadelphia chromosome refer to?
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