1. For parts (a), (b), and (c) of this problem, draw a diagram illustrating the alleles on homologous chromosomes for the genotypes given, assuming in each case that the genes reside on the chromosome in the order written. For parts (d) and (e), give the information requested. а. АB/ab b. aBc/abC c. DFg/DFG
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- 3) A. How are the following proteins involved in cell division: condensing, cohesin, kinetochore complex, tubulin? B. Why does phenotype not always reveal genotype? C. How can Mendel's postulates of segregation and independent assortment be explained by meiosis? D. Explain the genotypic and phenotypic ratios predicted when performing a monohybrid and a dihybrid cross of heterozygotes? E. How can you use the product rule and sum rule to calculate the probability of a particular genotype resulting from crossing parents of specific genotypes?1. Hair or fur length in cats is controlled by a single, autosomal gene; the short hair-allele is dominant to the allele for long hair. Hair color is produced by a different gene which is located on the X chromosome. One allele for this sex-linked gene produces yellow, while an alternate allele produces black fur color; individualswhich are heterozygous for these alleles are calico or tortiseshell in color.If a long-haired, black male is mated with a calico female homozygous for short hair what kind of kittens will be produced in the Ej generation? Give both genotypes and phenotypes; express the genotypes bothsymbolically and in words. Label answers clearly!!In Drosophila, a heterozygous female for the X-linkedrecessive traits a, b, and c was crossed to a male that phenotypically expressed a, b, and c. The offspring occurred inthe following phenotypic ratios.+ b c 460a + + 450a b c 32+ + + 38a + c 11+ b + 9 No other phenotypes were observed.(a) What is the genotypic arrangement of the alleles ofthese genes on the X chromosome of the female?
- 1. Take two coins and assume that heads represent the dominantallele (A) and tails represents the recessive allele (a). The genotype for each coin isheterozygous (Aa).2. Assume that each coin represents one parent. When a single coin is flipped, one gameteis formed (through the process of meiosis). If the flipped coin is on heads, then thegamete has the dominant allele (A). When both coins are flipped simultaneously, therewill be two possible gametes that can combine through fertilization to form a zygote. Eachtime you flip both coins, you will record the “genotype” of the offspring.3. Flip the coins 100 times and record your results in the chart below 4. Interpret the data in your tableConclusion:A woman who sought genetic counseling is found to be heterozygousfor a chromosomal rearrangement between the second andthird chromosomes. Her chromosomes, compared to those in anormal karyotype, are diagrammed on the next page:(a) This woman is phenotypically normal. Does thissurprise you? Why or why not? Under what circumstancesmight you expect a phenotypic effect of such arearrangement?Human females have two X chromosomes (XX); males have one X and one Y chromosome (XY). a. With respect to X-linked alleles, how many different types of gametes can a male produce? b. If a female is homozygous for an X-linked allele, how many types of gametes can she produce with respect to that allele? c. If a female is heterozygous for an X-linked allele, how many types of gametes can she produce with respect to that allele?
- In cats, the genotype AA produces tabby fur color; Aa is also a tabby, and aa is black. Another gene at a different locus is epistatic to the gene for fur color. When present in its dominant W form (WW or Ww), this gene blocks the formation of fur color and all the offspring are white; ww individuals develop normal fur color. What fur colors, and in what proportions, would you expect from the cross AaWw Aa Ww?Human females have two X chromosomes XX; males have one X and one Y chromosome XY. a. With respect to X-linked alleles, how many different types of gametes can a male produce? b. A female homozygous for an X-linked allele can produce how many types of gametes with respect to that allele? c. A female heterozygous for an X-linked allele can produce how many types of gametes with respect to that allele?The dominant C allele of a gene that controls color in corn produces kernels with color; plants homozygous for a recessive c allele of this gene have colorless or white kernels. What kinds of gametes, and in what proportions, would be produced by the plants in the following crosses? What seed color, and in what proportions, would be expected in the offspring of the crosses? a. CCCc b. Cccc c. CcCc
- Refer to problem 2. Assume a third gene has alleles C and c. For each genotype listed, what allele combinations will occur in gametes, assuming independent assortment? a. AABBCC b. AaBBcc c. AaBBCc d. AaBbCcAnother gene in Drosophila determines wing length. The dominant wild-type allele of this gene produces long wings; a recessive allele produces vestigial (short) wings. A female that is true- breeding for red eyes and long wings is mated with a male that has purple eyes and vestigial wings. F1 females are then crossed with purple-eyed, vestigial-winged males. From this second cross, a total of 600 offspring are obtained with the following combinations of traits: 252 with red eyes and long wings 276 with purple eyes and vestigial wings 42 with red eyes and vestigial wings 30 with purple eyes and long wings Are the genes linked, unlinked, or sex-linked? If they are linked, how many map units separate them on the chromosome?In addition to the two genes in problem 4, assume you now study a third independently assorting gene that has the alleles C and c. For each of the following genotypes, indicate what types of gametes will be produced: a. AA BB CC b. Aa BB Cc c. Aa BB cc d. Aa Bb Cc