220. Dr. Rose Lees is a world expert on breast cancer. Choose True or False. Of all the receptors involved, the HER2+ has a worse prognosis. [Choose ] [Choose]

Biology 2e
2nd Edition
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark
Chapter16: Gene Expression
Section: Chapter Questions
Problem 22RQ: Targeted therapies are used in patients with a set gene expression pattern. A targeted therapy that...
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Q20. Dr. Rose Lees is a world expert on breast cancer. Choose True or False.
Of all the receptors involved, the HER2+ has a worse
[ Choose ]
prognosis.
[ Choose ]
BRCA1 helps repair damaged DNA, or destroy cells if
DNA cannot be repaired.
True
False
The nuclear hormone receptors contain a DNA binding
domain towards the C-terminus.
[Choose]
The nuclear hormone receptors contain a ligand binding
domain toward the C-terminus.
[ Choose]
The main function of the estrogen receptor is as a DNA
binding transcription factor.
[ Choose ]
The last a-helix, helix 12, folds into a groove on the side
of the structure upon ligand binding.
[Choose ]
Upon binding of tamoxifen to the estrogen receptor, helix
12 exposes the coactivator-binding site.
[ Choose ]
>
Transcribed Image Text:Q20. Dr. Rose Lees is a world expert on breast cancer. Choose True or False. Of all the receptors involved, the HER2+ has a worse [ Choose ] prognosis. [ Choose ] BRCA1 helps repair damaged DNA, or destroy cells if DNA cannot be repaired. True False The nuclear hormone receptors contain a DNA binding domain towards the C-terminus. [Choose] The nuclear hormone receptors contain a ligand binding domain toward the C-terminus. [ Choose] The main function of the estrogen receptor is as a DNA binding transcription factor. [ Choose ] The last a-helix, helix 12, folds into a groove on the side of the structure upon ligand binding. [Choose ] Upon binding of tamoxifen to the estrogen receptor, helix 12 exposes the coactivator-binding site. [ Choose ] >
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