3) Now put this information to use.... suggest a synthesis of 13b, a peptidomimetic inhibitor of the SARS-CoV-2 MPro enzyme, a key protease enzyme vital to the life cycle of the virus that causes COVID-19. The virus expresses its proteins (including the famous spike protein, membrane proteins, proteins to hold the RNA and proteins responsible for replication) in two large polypeptides. The MPro enzyme acts like a scissors and cuts one of these large polypeptides apart into the individual active proteins. The inhibitor 13b covalently modifies the enzyme, prevents the release of the individual proteins and therefore inhibits the virus. HạN он HạN HO. 13b HN peptidomimetic inhibitor of SARS-CoV-2-MPro

3) Now put this information to use.... suggest a synthesis of 13b, a peptidomimetic inhibitor of the SARS-CoV-2 MPro enzyme, a key protease enzyme vital to the life cycle of the virus that causes COVID-19. The virus expresses its proteins (including the famous spike protein, membrane proteins, proteins to hold the RNA and proteins responsible for replication) in two large polypeptides. The MPro enzyme acts like a scissors and cuts one of these large polypeptides apart into the individual active proteins. The inhibitor 13b covalently modifies the enzyme, prevents the release of the individual proteins and therefore inhibits the virus. HạN он HạN HO. 13b HN peptidomimetic inhibitor of SARS-CoV-2-MPro

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter16: Reproductive Technology, Genetic Testing, And Gene Therapy

Section: Chapter Questions

Problem 13QP: The prospect of using gene therapy to alleviate genetic conditions is still a vision of the future....

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