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3' -T ACATC T T G G C GAC GAC T-5' Mutated DNA Sequence #1: MRNA sequence? (Circle the change) Amino acid sequence? Effects? What kind of mutation is this? 3'-ТАCGA ссттсGсGACGACT-5' Mutated DNA Sequence #2: MRNA sequence? (circle the change) Amino acid sequence? Effects? What kind of mutation is this? 3' -T A CACCTTAG C G AC GAC T-5' Mutated DNA Sequence #3: MRNA sequence? (Circle the change) Amino acid sequence? Will there likely be effects? What kind of mutation is this? 3' -T ACACCT T G G C G A CTAC T-5' Mutated DNA Sequence #4: MRNA sequence? (circle the change) Amino acid sequence? Will there likely be effects? What kind of mutation is this? 3' -T A CA CCT T G A C GAC GAC T-5' Mutated DNA Sequence #5: MRNA sequence? (circle the change) Amino acid sequence? Will there likely be effects? What kind ofmutation is this?

3' -T ACATC T T G G C GAC GAC T-5' Mutated DNA Sequence #1: MRNA sequence? (Circle the change) Amino acid sequence? Effects? What kind of mutation is this? 3'-ТАCGA ссттсGсGACGACT-5' Mutated DNA Sequence #2: MRNA sequence? (circle the change) Amino acid sequence? Effects? What kind of mutation is this? 3' -T A CACCTTAG C G AC GAC T-5' Mutated DNA Sequence #3: MRNA sequence? (Circle the change) Amino acid sequence? Will there likely be effects? What kind of mutation is this? 3' -T ACACCT T G G C G A CTAC T-5' Mutated DNA Sequence #4: MRNA sequence? (circle the change) Amino acid sequence? Will there likely be effects? What kind of mutation is this? 3' -T A CA CCT T G A C GAC GAC T-5' Mutated DNA Sequence #5: MRNA sequence? (circle the change) Amino acid sequence? Will there likely be effects? What kind ofmutation is this?

Biology: The Dynamic Science (MindTap Course List)
Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Chapter15: From Dna To Protein
Section: Chapter Questions
Problem 10TYK: A part of an mRNA molecule with the sequence 5-UGC GCA-3 is being translated by a ribosome. The...
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3' -T ACATC T T G G C GAC GAC T-5' Mutated DNA Sequence #1: MRNA sequence? (Circle the change) Amino acid sequence? Effects? What kind of mutation is this? 3'-ТАCGA ссттсGсGACGACT-5' Mutated DNA Sequence #2: MRNA sequence? (circle the change) Amino acid sequence? Effects? What kind of mutation is this? 3' -T A CACCTTAG C G AC GAC T-5' Mutated DNA Sequence #3: MRNA sequence? (Circle the change) Amino acid sequence? Will there likely be effects? What kind of mutation is this? 3' -T ACACCT T G G C G A CTAC T-5' Mutated DNA Sequence #4: MRNA sequence? (circle the change) Amino acid sequence? Will there likely be effects? What kind of mutation is this? 3' -T A CA CCT T G A C GAC GAC T-5' Mutated DNA Sequence #5: MRNA sequence? (circle the change) Amino acid sequence? Will there likely be effects? What kind ofmutation is this?
Transcribed Image Text:3' -T ACATC T T G G C GAC GAC T-5' Mutated DNA Sequence #1: MRNA sequence? (Circle the change) Amino acid sequence? Effects? What kind of mutation is this? 3'-ТАCGA ссттсGсGACGACT-5' Mutated DNA Sequence #2: MRNA sequence? (circle the change) Amino acid sequence? Effects? What kind of mutation is this? 3' -T A CACCTTAG C G AC GAC T-5' Mutated DNA Sequence #3: MRNA sequence? (Circle the change) Amino acid sequence? Will there likely be effects? What kind of mutation is this? 3' -T ACACCT T G G C G A CTAC T-5' Mutated DNA Sequence #4: MRNA sequence? (circle the change) Amino acid sequence? Will there likely be effects? What kind of mutation is this? 3' -T A CA CCT T G A C GAC GAC T-5' Mutated DNA Sequence #5: MRNA sequence? (circle the change) Amino acid sequence? Will there likely be effects? What kind ofmutation is this?
Mutations Exercises You are given the template sequence of an original DNA, and several mutations in the template (on the next page). Figure out the MRNA sequence and protein sequence of each template, and then determine the type of mutation that occurred, relative to the original sequence. Choose from the following mutational types. Classify each mutation at both the DNA and protein level: A. DNA level a. Point mutation - transition b. Point mutation – transversion c. Frameshift B. Protein level a. Synonymous b. Nonsynonymous – missense c. Nonsynonymous - nonsense d. Frameshift THE GENETIC CODE SECOND LETTER A G UuU Phe Uuc UAU Tyr UGU) Cys UGC) UcC UAC) Ser UA Leu UUG) UAA Ochre (terminator) Оpal terminator UCA UGA A UCG) UAG Amber (terminator) UGG Trp G CU CAU) His САС CU CGU CUC CGC Arg CGA Leu Pro CUA CCA САА Gin CUG, CCG CAG CGG/ ACU AGU) Ser AGC) AUU AAU AUC lleu A Asn AAC ACC Thr AGA AUA АCА AAA Lys AAG Arg Met AUG ACG AGG) (initiator) GCU GAU Asp GAC GUU GGU GUC Val GUA GCC Ala GCA GGC Gly GGA GAA Glu GAG) A GUG) (initiator) GCG/ GGG G Original DNA Sequence: MRNA Sequence: 3'-T ACACCTT G CGACT-5' 5'-A UG UGGAA cCG CUG CUGA-3' Amino Acid Sequence: Met - Trp - Asn - Arg Cys - STOP FIRST (5') LETTER THIRD (3') LETTER
Transcribed Image Text:Mutations Exercises You are given the template sequence of an original DNA, and several mutations in the template (on the next page). Figure out the MRNA sequence and protein sequence of each template, and then determine the type of mutation that occurred, relative to the original sequence. Choose from the following mutational types. Classify each mutation at both the DNA and protein level: A. DNA level a. Point mutation - transition b. Point mutation – transversion c. Frameshift B. Protein level a. Synonymous b. Nonsynonymous – missense c. Nonsynonymous - nonsense d. Frameshift THE GENETIC CODE SECOND LETTER A G UuU Phe Uuc UAU Tyr UGU) Cys UGC) UcC UAC) Ser UA Leu UUG) UAA Ochre (terminator) Оpal terminator UCA UGA A UCG) UAG Amber (terminator) UGG Trp G CU CAU) His САС CU CGU CUC CGC Arg CGA Leu Pro CUA CCA САА Gin CUG, CCG CAG CGG/ ACU AGU) Ser AGC) AUU AAU AUC lleu A Asn AAC ACC Thr AGA AUA АCА AAA Lys AAG Arg Met AUG ACG AGG) (initiator) GCU GAU Asp GAC GUU GGU GUC Val GUA GCC Ala GCA GGC Gly GGA GAA Glu GAG) A GUG) (initiator) GCG/ GGG G Original DNA Sequence: MRNA Sequence: 3'-T ACACCTT G CGACT-5' 5'-A UG UGGAA cCG CUG CUGA-3' Amino Acid Sequence: Met - Trp - Asn - Arg Cys - STOP FIRST (5') LETTER THIRD (3') LETTER
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