3rd question You are a formulation scientist preparing a semisolid topical scream. Your formulation requires that a 1000 mL solvent of pH 7.4 phosphatebuffer be prepared to suit the pH of the skin. To prepare the buffer, you must use monobasic sodium phosphate (NAH2PO4) and sodiumhydroxide (NAOH) since these two ingredients are compatible with your other ingredients in the cream.NaH2PO4 + NаОН — Na2HPО4 + H201. The Ka of NaH2PO4 6.2 x 10-8. Using the Henderson-Hasselbalch equation, calculate the molar ratio of [conjugate base]/[weak acid] thatmust be used in preparing the buffer.A.0.39В. 0.78C. 1.56D. 2.342. There is an available 50 mL of 0.2M NAH2PO4 in the laboratory. Convert this first to the moles of NaH2P04. The molar mass of NaH2PO4 is119.98 g/mol.A.0.005 mol B. 0.010 molC. 0.025 molD. 0.045 mol3. Given the number of moles of NAH2PO4 available as computed above and the molar ratio calculated, which of the following moles of NaOHwhen added to NAH2PO4 will produce the required bufferА.0.0061 molB. 0.0078 molC. 0.0156 molD. 0.0390 mol4. If a readily available 0.2 M NaOH is present in the lab, how many mL of this solution will you use to supply the calculated moles from above?А.30.5 mLB. 39.0 mLC. 78.0 mLD. 195.0 mL

Given, Volume of NaH2PO4 = 50 mL Molarity of NaH2PO4 = 0.2 M Molar mass of NaH2PO4 = 119.98…

3. Given the number of moles of NaH2PO4 available as computed above and the molar ratio calculated, which of the following moles of NaOH when added to NaH2PO4 will produce the required buffer A. 0.0061 mol B. 0.0078 mol C. 0.0156 mol D. 0.0390 mol

3. Given the number of moles of NaH2PO4 available as computed above and the molar ratio calculated, which of the following moles of NaOH when added to NaH2PO4 will produce the required buffer A. 0.0061 mol B. 0.0078 mol C. 0.0156 mol D. 0.0390 mol

Chemistry: Principles and Reactions

8th Edition

ISBN:9781305079373

Author:William L. Masterton, Cecile N. Hurley

Publisher:William L. Masterton, Cecile N. Hurley

Chapter14: Equilibria In Acid-base Solutions

Section: Chapter Questions

Problem 25QAP: A sodium hydrogen carbonate-sodium carbonate buffer is to be prepared with a pH of 9.40. (a) What...

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Question

3rd question

You are a formulation scientist preparing a semisolid topical scream. Your formulation requires that a 1000 mL solvent of pH 7.4 phosphate
buffer be prepared to suit the pH of the skin. To prepare the buffer, you must use monobasic sodium phosphate (NAH2PO4) and sodium
hydroxide (NAOH) since these two ingredients are compatible with your other ingredients in the cream.
NaH2PO4 + NаОН — Na2HPО4 + H20
1. The Ka of NaH2PO4 6.2 x 10-8. Using the Henderson-Hasselbalch equation, calculate the molar ratio of [conjugate base]/[weak acid] that
must be used in preparing the buffer.
A.
0.39
В. 0.78
C. 1.56
D. 2.34
2. There is an available 50 mL of 0.2M NAH2PO4 in the laboratory. Convert this first to the moles of NaH2P04. The molar mass of NaH2PO4 is
119.98 g/mol.
A.
0.005 mol B. 0.010 mol
C. 0.025 mol
D. 0.045 mol
3. Given the number of moles of NAH2PO4 available as computed above and the molar ratio calculated, which of the following moles of NaOH
when added to NAH2PO4 will produce the required buffer
А.
0.0061 mol
B. 0.0078 mol
C. 0.0156 mol
D. 0.0390 mol
4. If a readily available 0.2 M NaOH is present in the lab, how many mL of this solution will you use to supply the calculated moles from above?
А.
30.5 mL
B. 39.0 mL
C. 78.0 mL
D. 195.0 mL

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