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- Cytokine Storm (Cytokine Storm) COVID-19The high mortality rate in COVID-19 patients is caused by the occurrence of a cytokine storm (cytokine storm) in the patient's body. This is based on research supported by data obtained, among others, from laboratory results; that there was a significant difference between patients who recovered and those who died. What research data? Please Answer these following structured questions; Are cytokines a protein? How many amino acid residues of human cytokines? The sequence of the amino acid residues? Accession number at GenBank ? Determine the mRNA sequence Determine the coding sequence Define the sequence template What is a Cytokine storm What research data support the occurrence of Cytokine storm in humans Answers on paper with source cited provided will be helpful since im new in this part and want to learn from the source you find the answer Thank youA gel filtration column with a fractionation range of 1.5-20 kDa is used to separate out the proteins shown below. If these proteins are collected into separate fractions in between the void volume and total volume, in which order will they elute? Indicate if any of the proteins are found in the void volume or total volume fractions. Protein Z - 3330Da Protein Y - 13kDa Protein X - 1.3kDa I. Total volume fraction II. Third protein fraction III. Second protein fraction IV. First protein fraction V. Void volume fractionPlease pick among these 4 Protein chromatography is typically column-based:— lon-exchange— Reverse-phase/Hydrophobic interaction— Gel-filtration— Affinity
- Enzyme chymotrypsin (enzyme digest) Samples: - 1 & 5- Standard Protein (Ladder) - 2 & 6- UNCUT (tube #1) - 3 & 7- 5 mins (tube #2) - 4 & 8- 30 mins (tube #3) Human and Bovine (Left) Chicken and Pigeon (Right) In this experiment we will be comparing the structural similarity of serum albumin from several different vertebrate species and thus examining how closely related the proteins from these species are to each other. These proteins have similar molecular weights. We will first cut the proteins with the enzyme chymotrypsin (enzyme digest). We will then separate the fragments based on their relative sizes through gel electrophoresis so that we can compare the fragments generated by the enzyme digest for the different species. Write the hypothesis and prediction for the experiment.Classify the symmetrical arrangement ofthe subunits (e.g., C2 , C3 , D 2 , helical, icosahedral). 1. Proteobacterial nitrite sensor (3PNS):2. Pseudomonad oligosaccharide receptor (7POR):3. Adenoviral structural protein (8ASP)L--L--F--A--I--A--M--F--L--N--I--A--I--A--I What do you think will happen if large concentrations of the given peptide above are mixed in an aqueous buffer?
- Define the following terms:a. rough ERb. smooth ERc. clathrind. unfolded protein responsee. caveolaeExperiment: Action of Pancreatic Proteases and Trypsin on Protein Procedure: B. Action of Pancreatic Proteases and Trypsin on Protein1. Prepare 3 test tubes containing 2 mL egg albumin solution.Tube 1: Add 1 mL 5% TrypsinTube 2: Add 1 mL 5% Trypsin and 2 mL of 0.5% Na2CO3 SolutionTube 3: Add 2 mL 0.5% Na2CO3 Solution2. Place all test tubes in hot water bath maintained at 38-40°C for one hour.3. Filter the contents of each test tube and use the filtrate for biuret test. Question: What are the possible color change that can be observed in the experiment? In which of the test tubes did hydrolysis of protein take place?Consider the following peptide sequence: Lys-Leu-Ile-Cys-Lys What is the net charge of this sequence at physiological pH? a. -2 b. +1 c. 0 d. -1 e. +2
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