Homework Help is Here – Start Your Trial Now!
Science
Biochemistry
5. Indicate which one of the following statements is not correct: a. Drugs that are taken up into the body through the gastrointestinal mucosa will be transported to the liver via the portal vein before going into general circulation. b. If the drug is susceptible to metabolic degradation in the liver, this may considerably enhance the activity of the drug. This phenomenon is known as the hepatic first-pass effect. c. Therectal route may also show varying degrees of the first-pass effect. d. In other routes of administration (intravenous, vaginal, nasal, buccal and sublingual) the drug is distributed in the body before reaching the liver. Whilst the liver is the main metabolic organ of the body, metabolism may also take place in the gastrointestinal lumen and indeed in the е. mucosal membranes.

5. Indicate which one of the following statements is not correct: a. Drugs that are taken up into the body through the gastrointestinal mucosa will be transported to the liver via the portal vein before going into general circulation. b. If the drug is susceptible to metabolic degradation in the liver, this may considerably enhance the activity of the drug. This phenomenon is known as the hepatic first-pass effect. c. Therectal route may also show varying degrees of the first-pass effect. d. In other routes of administration (intravenous, vaginal, nasal, buccal and sublingual) the drug is distributed in the body before reaching the liver. Whilst the liver is the main metabolic organ of the body, metabolism may also take place in the gastrointestinal lumen and indeed in the е. mucosal membranes.

Biology: The Dynamic Science (MindTap Course List)
Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Chapter47: Animal Nutrition
Section: Chapter Questions
Problem 6TYK
See similar textbooks
icon
Related questions
Question
5. Indicate which one of the following statements is not correct: a. Drugs that are taken up into the body through the gastrointestinal mucosa will be transported to the liver via the portal vein before going into general circulation. b. If the drug is susceptible to metabolic degradation in the liver, this may considerably enhance the activity of the drug. This phenomenon is known as the hepatic first-pass effect. c. Therectal route may also show varying degrees of the first-pass effect. d. In other routes of administration (intravenous, vaginal, nasal, buccal and sublingual) the drug is distributed in the body before reaching the liver. Whilst the liver is the main metabolic organ of the body, metabolism may also take place in the gastrointestinal lumen and indeed in the е. mucosal membranes.
Transcribed Image Text:5. Indicate which one of the following statements is not correct: a. Drugs that are taken up into the body through the gastrointestinal mucosa will be transported to the liver via the portal vein before going into general circulation. b. If the drug is susceptible to metabolic degradation in the liver, this may considerably enhance the activity of the drug. This phenomenon is known as the hepatic first-pass effect. c. Therectal route may also show varying degrees of the first-pass effect. d. In other routes of administration (intravenous, vaginal, nasal, buccal and sublingual) the drug is distributed in the body before reaching the liver. Whilst the liver is the main metabolic organ of the body, metabolism may also take place in the gastrointestinal lumen and indeed in the е. mucosal membranes.
Expert Solution
steps

Step by step

Solved in 2 steps

SEE SOLUTIONCheck out a sample Q&A here
Blurred answer
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Biology: The Dynamic Science (MindTap Course List)
Biology: The Dynamic Science (MindTap Course List)
Biology
ISBN:
9781305389892
Author:
Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:
Cengage Learning
Anatomy & Physiology
Anatomy & Physiology
Biology
ISBN:
9781938168130
Author:
Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble
Publisher:
OpenStax College
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Fundamentals of Sectional Anatomy: An Imaging App…
Fundamentals of Sectional Anatomy: An Imaging App…
Biology
ISBN:
9781133960867
Author:
Denise L. Lazo
Publisher:
Cengage Learning
Biology: The Unity and Diversity of Life (MindTap…
Biology: The Unity and Diversity of Life (MindTap…
Biology
ISBN:
9781305073951
Author:
Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
Publisher:
Cengage Learning
SEE MORE TEXTBOOKS