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- Describe the effects caused when the parathyroid gland fails to respond to calcium bound to its receptors.Compare and contrast the signaling events involved with the second messengers cAMP and IP3.The end result of the RAAS is to ________. reduce blood volume increase blood glucose reduce blood pressure increase blood pressure
- What is the maximum allowable dosage of the most commonly used anesthetic solution i.e. 2% Lidocaine HCl with 1:100,000 epinephrine for a 52 kg healthy adult?48) Opioid receptor antagonist administration should be avoided in pregnancy unless absolutely needed, because death of the fetus could result from _______________. 48) Vasodilation Narcotic Withdrawal Malnutrition Acidity(28)The bioavailability of drug X after oral administration is 38%. Which of the following best explains this level of systematic bioavailability?? (A) Adipose distribution. (B) Hepatic Metabolism. (C) Plasma Protein Binding. (D) Pulmonary Metabolism. (E) Renal Metabolism
- 80. An investigator is studying the effects of a hormone in two groups of experimental animals. During a 2-hour period, Group X receives an infusion of 0.9% saline and Group Y receives an infusion of the hormone. The following findings are recorded: Group X Group Y Pulse 380/min 550/min Mean arterial blood pressure Serum 120 mm Hg 150 mm Hg Glucose 80 mg/dL 130 mg/dL Free fatty acids 3.5 JEq/L 7.5 JEq/L Plasma renin 2.5 ng/ml/h 18 ng/mL/h Group Y most likely received which of the following hormones? A) ADH (vasopressin) B ) Aldosterone C ) Cortisol D) Epinephrine E) Glucagon F) Growth hormone G) Thyroxine (T 4)Two steps in the synthesis of tadalafil, a drug sold under the trade nameCialis for the treatment of erectile dysfunction, are shown. Identifyintermediate A, and draw a mechanism for the conversion of A totadalafil.The loading dose of indomethacin in neonates is 0.2 mg/kg of body weight by intravenous infusion. a. What would be the dose for a neonate weighing 6 lb 4 oz? b. How many milliliters of an injection containing 1 mg of indomethacin per 0.5 mL should be administered to obtain this dose?
- neurokinin-1 receptor antagonists known to inhibit the CYP3A4 enzyme. There is a potential drug drug interaction between lopinavir/ritonavir combination and aprepitant. Explain the potential pharmacokinetic consequences of the interaction on PK parameters of lopinavir and ritonavir following oral administration. AUC, apparent volume of distribution, clearance.One of the initial symptoms a person can have for COVID-19 is the lost of taste and smell. Give a potential mechanism, including which portion of the reflex arc is being impacted, of how COVID is able to have this impact. Use an online source to support your argument.what possible outcome may be produced when the molecular weight of an alcohol antiseptic is increase to a C20, will it still be effective? Explain your answer