6. Mass spectrometry and UV/Vis absorbance spectroscopy can both be used as detectors for liquid chromatography experiments. a. In simple systems, quantifying the concentration of an analyte is usually easier with U'V/Vis than with MS. Explain why. b. Because MS is more sensitive and more selective, we often use it for quantitative analysis anyway. Explain how you would design a quantitative LC/MS experiment.
6. Mass spectrometry and UV/Vis absorbance spectroscopy can both be used as detectors for liquid chromatography experiments. a. In simple systems, quantifying the concentration of an analyte is usually easier with U'V/Vis than with MS. Explain why. b. Because MS is more sensitive and more selective, we often use it for quantitative analysis anyway. Explain how you would design a quantitative LC/MS experiment.
Chapter33: High-performance Liquid Chromatography
Section: Chapter Questions
Problem 33.12QAP
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