6. Morphine (structure shown) is a prescription-strength analgesic used to treat severe pain. pk. = 9.90 но, pks = 8.20 HO a) At the pH of human blood plasma (pH 7.4), what is the charge on the -OH group (with pKa = 9.90)? Circle one: positive neutral negative b) At the pH of human blood plasma (pH 7.4), what is the charge on the amino group (with pKb = 8.20)? Circle one: positive neutral negative c) At what pH would morphine be the least polar: pH 4.0, 7.0, or 11.0? Circle one: 4.0 7.0 11.0 Briefly explain:

Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter4: Acids And Bases
Section: Chapter Questions
Problem 4.33P: Complete the equation for the reaction between each Lewis acid-base pair. In each equation, label...
icon
Related questions
icon
Concept explainers
Question
6. Morphine (structure shown) is a prescription-strength analgesic used to treat severe pain.
pKa = 9.90
> HO.
pKb = 8.20
HO"
a) At the pH of human blood plasma (pH 7.4), what is the charge on the -OH group (with
pKa = 9.90)? Circle one: positive
neutral
negative
b) At the pH of human blood plasma (pH 7.4), what is the charge on the amino group
(with pkb = 8.20)? Circle one: positive
neutral
negative
c) At what pH would morphine be the least polar: pH 4.0, 7.0, or 11.0?
Circle one: 4.0
7.0
11.0
Briefly explain:
Transcribed Image Text:6. Morphine (structure shown) is a prescription-strength analgesic used to treat severe pain. pKa = 9.90 > HO. pKb = 8.20 HO" a) At the pH of human blood plasma (pH 7.4), what is the charge on the -OH group (with pKa = 9.90)? Circle one: positive neutral negative b) At the pH of human blood plasma (pH 7.4), what is the charge on the amino group (with pkb = 8.20)? Circle one: positive neutral negative c) At what pH would morphine be the least polar: pH 4.0, 7.0, or 11.0? Circle one: 4.0 7.0 11.0 Briefly explain:
Expert Solution
steps

Step by step

Solved in 4 steps with 2 images

Blurred answer
Knowledge Booster
Ionic Equilibrium
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Organic Chemistry
Organic Chemistry
Chemistry
ISBN:
9781305580350
Author:
William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:
Cengage Learning
Organic Chemistry
Organic Chemistry
Chemistry
ISBN:
9781305080485
Author:
John E. McMurry
Publisher:
Cengage Learning
Organic Chemistry: A Guided Inquiry
Organic Chemistry: A Guided Inquiry
Chemistry
ISBN:
9780618974122
Author:
Andrei Straumanis
Publisher:
Cengage Learning