A biotech company develops a biosensor that measures the presence of proteins activated by growth factor signaling cascades. Which binding domain would you use to each of the following activation peptides or signaling molecules. ◆ Phosphotyrosine A. SH2 Domain A peptide with the sequence Arg-Ala-Pro-Pro-Leu- B. Bromodomain Pro C. 14-3-3 Domain ◆ Phosphatidyl inositol Triphosphate (PIP3) Phosphoserine ◆ Acetylated Lysine D.PH Domain E. SH3 Domain

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter32: The Reception And Transmission Of Extracellular Information
Section: Chapter Questions
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A biotech company develops a biosensor that measures the presence of proteins activated by growth factor signaling
cascades. Which binding domain would you use to each of the following activation peptides or signaling molecules.
Phosphotyrosine
A. SH2 Domain
A peptide with the sequence Arg-Ala-Pro-Pro-Leu- B. Bromodomain
Pro
C. 14-3-3 Domain
◆ Phosphatidyl inositol Triphosphate (PIP3)
Phosphoserine
Acetylated Lysine
D.PH Domain
E. SH3 Domain
Transcribed Image Text:A biotech company develops a biosensor that measures the presence of proteins activated by growth factor signaling cascades. Which binding domain would you use to each of the following activation peptides or signaling molecules. Phosphotyrosine A. SH2 Domain A peptide with the sequence Arg-Ala-Pro-Pro-Leu- B. Bromodomain Pro C. 14-3-3 Domain ◆ Phosphatidyl inositol Triphosphate (PIP3) Phosphoserine Acetylated Lysine D.PH Domain E. SH3 Domain
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