A biotechnology company discovers a bacterium isolated from waste industry that produces protease that can operate at high pH. Such protease is useful in making heavy duty detergent that has high pH catalytic condition. Thus, the company decided to produce the protease at large scale using bioreactors. a) Discuss how this is possible when the bacterium is difficult to grow and produce the protease at low level. Suggest any means to overcome these difficulties. b) Suggest what type of bioreactor and mode of culture that is suitable for the production of protease at large scale. Justify your answer.
A biotechnology company discovers a bacterium isolated from waste industry that produces protease that can operate at high pH. Such protease is useful in making heavy duty detergent that has high pH catalytic condition. Thus, the company decided to produce the protease at large scale using bioreactors. a) Discuss how this is possible when the bacterium is difficult to grow and produce the protease at low level. Suggest any means to overcome these difficulties. b) Suggest what type of bioreactor and mode of culture that is suitable for the production of protease at large scale. Justify your answer.
Basic Clinical Laboratory Techniques 6E
6th Edition
ISBN:9781133893943
Author:ESTRIDGE
Publisher:ESTRIDGE
Chapter7: Basic Clinical Microbiology
Section7.7: Bacterial Identification And Antibiotic Susceptibility Testing
Problem 3CS
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Transcribed Image Text:A biotechnology company discovers a bacterium isolated from waste industry that produces
protease that can operate at high pH. Such protease is useful in making heavy duty detergent
that has high pH catalytic condition. Thus, the company decided to produce the protease at
large scale using bioreactors.
a) Discuss how this is possible when the bacterium is difficult to grow and produce the
protease at low level. Suggest any means to overcome these difficulties.
b) Suggest what type of bioreactor and mode of culture that is suitable for the production of
protease at large scale. Justify your answer.
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