A common misconception about mutations is that they are always harmful. What mutation effects on an organism? οιοιοιο Mutations can be harmful, neutral, or beneficial, and they drive genetic variation Mutations are always harmful and decrease genetic variation Mutations are always neutral and have no effect on genetic variation Mutations are always beneficial and increase genetic variation
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- The reason spontaneous mutations do not have an immediate effect on allele frequencies in a large population is that: a. mutations are random events, and mutations may be eitherbeneficial or harmful. b. mutations usually occur in males and have little effect oneggs. c. many mutations exert their effects after an organism hasstopped reproducing. d. mutations are so rare that mutated alleles are greatlyoutnumbered by nonmutated alleles. e. most mutations do not change the amino acid sequence of aprotein.When comparing genomes from 2 different organisms, "regions of synteny" refers to...• Whether the number of chromosomes is similar• blocks of sequence where the same genes are present in the same order• Alleles that are inherited together without following the Law of Independent Assortment• Segments that contain genes present in one organism but absent in the other• Regions with 100% sequence similarityA dominant allele that arises from recurrent mutation is mildly deleterious. The fitness of heterozygotes is 99% of normal. The phenotype appears in about 1 out of every 10,000 newborns. What is the allele frequency? Assuming that there is a mutation/selection balance, estimate the mutation rate. (this is all the information given on the question
- Human geneticists have found the Finnish populationto be very useful for studies of a variety of conditions.The population is small; Finns have extensive churchrecords documenting lineages; and few people havemigrated into Finland. The frequency of some recessive disorders is higher in the Finnish population thanelsewhere in the world, and diseases such as PKU andcystic fibrosis that are common elsewhere do not occur in the Finnish population.a. How would a population geneticist explain thesevariations in disease occurrence?b. The Finnish population is also a source ofinformation for the study of quantitative traits. Thegenetic basis of schizophrenia is one question that canbe explored in this population. What advantage(s) anddisadvantage(s) can you imagine for studying complex traits based on the Finnish population structure?Some genetic disorders are caused by autosomal recessive alleles. Many such alleles are recessive lethals, causing lethality very early in life (say, before the age of 20 yrs). Intuitively one might suggest that selection working on human population should completely remove such alleles from the population. Yet, there are many examples of such lethal genetic disorders occurring in low frequency in several human populations. Why is it almost impossible to completely remove these seemingly fitness-detrimental alleles from the population? Under what condition, extinction of such an allele from a population can be achieved?Artificial selection is when people selectively choose individuals with a certain desired trait to use as parents of the next generation. It is done to domesticated (or semi-domesticated) organisms. It has produced such monstrosities as bubble-eyed goldfish, revealing the potential for selection acting on heritable variation to produce varieties appearing very different than their ancestors. How is that different from natural selection? (Select all that apply) A- In artificial selection, humans directly cause new mutations to occur, whereas natural selection relies on mutations that occur randomly over time. B- Artificial selection can lead to organisms that would be unfit to survive in the wild, whereas natural selection usually makes the population better adapted. C- Artificial selection is directed ahead of time towards an intentional goal; not so with natural selection. D- Really, they are exactly the same process. Both cause what seems to be design without a designer. E-…
- What is genetic flow? A) Genes changing due to mutation B) Random loss of genes in a small population C) Movement of genes between different populationsHow can you use this piece of information to help you explain to your friends what is the significance of mutations in the emergence of new genetic properties (alleles) that may result (or not) in new phenotypic characteristics? (Recall that not all SNPs affect phenotype.)Imagine a population of mice living in a grey, rocky environment. Some mice are grey and some are brown. If natural selection occurs in this population, what would you expect to see if you returned in 100 mouse generations? Describe what you'd see in terms of fur colors in the population. Imagine a population of mice living in a grey, rocky environment. Some mice are grey and some are brown. If mutations occur in this population, what could you see if you returned in 100 mouse generations, that would tell you mutations had occurred? Describe what you'd see in terms of fur colors in the population, and how it would be different from what you'd see in #2.
- The zebra fish is a very popular aquarium pet fish that is known to be hardy, attractive, and able to survive well in groups. Wild type zebra fish have blue–purple horizontal stripes that run from gill to tail, with a silver–gold body. An alternative form of the zebra fish results from a mutation that causes a homozygous recessive red-colour fish. Could you kindly answer all of the questions? It's multiple choice so minimal explanation is needed and i do not have a lot of questions left. Thank you. a) If 32 of 84 zebra fish have the recessive phenotype of red colour, what is the frequency of the recessive allele in this population of fish? a. 0.62 b. 0.38 c. 0.14 d. 0.79 b) What percentage of the population of zebra fish are heterozygous? a. 47% b. 38% c. 62% d. 53% c)How many zebra fish are purebreeding for the blue–purple horizontal stripes? a. 72 b. 12 c. 52 d. 5 d) If 15 years ago, 34 of 88 zebra fish had the red colour, has microevolution occurred? Why or why not?…You are studying two genetic loci that are on the same chromosome. One of the loci is a gene that produces darker feathers in dark environments in birds. The second locus is a gene associated with metabolism. In your research you find that the second locus is not under selection, but the first locus is undergoing positive selection. The positive selection at the first locus is increasing a specific allele at the second locus. This discovery of yours is best described as which of the following? a. Recombinaton b. Linkage equilibrium c. Genetic hitchhiking d. Chromosome inversionA form of learning disabilities and speech impairment results from a recessive mutation in the HERC2 gene. The next 4 questions are about this mutation. In a small Amish village in Ohio, about 5 per 1000 births are affected with this disorder. Assume Hardy Weinberg equilibrium. What is the frequency of the dominant WT HERC2 allele in this small village? A form of learning disabilities and speech impairment results from a recessive mutation in the HERC2 gene. The next 4 questions are about this mutation. Part a: In a small Amish village in Ohio, about 5 per 1000 births are affected with this disorder. Assume Hardy Weinberg equilibrium. What is the frequency of the dominant WT HERC2 allele in this small village? a)0.005 b)0.995 c)0.07 d)0.93 Part b: What is the estimated total number of homozygous dominant individuals in this village of 1000 people? a) 70 b) 930 c) 860 d) 140