A geneticist induces a mutation in a cell line growing in the laboratory. The mutation occurs in a gene that encodes a protein that binds to the poly(A) tail of eukaryotic mRNA. What will be the immediate effect of this mutation in the cultured cells?

A geneticist induces a mutation in a cell line growing in the laboratory. The mutation occurs in a gene that encodes a protein that binds to the poly(A) tail of eukaryotic mRNA. What will be the immediate effect of this mutation in the cultured cells?

Name: A geneticist induces a mutation in a cell line growing in the laborato
Uploaded: 2024-03-20T06:42:55.000Z
Channel: Bartleby
Description: A geneticist induces a mutation in a cell line growing in the laboratory. The mutation occurs in a gene that encodes a protein that binds to the poly(A) tail of eukaryotic mRNA. What will be the immediate effect of this mutation in the cultured cells

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter11: Genome Alterations: Mutation And Epigenetics

Section: Chapter Questions

Problem 10QP: If the coding region of a gene (the exons) contains 2,100 base pairs of DNA, would a missense...

See similar textbooks

Similar questions

The length of a particular gene in human DNA, measured from the start site for transcription to the end of the protein-coding region, is 10,000 nucleotides, whereas the length of the mRNA produced from this gene is 4000 nucleotides. What is the most likely reason for this difference?
Geneticists have found that when they cut out a eukaryotic gene from genomic DNA that they can hybridize one of the strands of that gene to the mRNA for that gene by allowing the strands to hydrogen bond. Why is it sometimes claimed that alternative splicing of exons from a single gene results in a set of proteins of related function?
What is the name of the enzyme is responsible for transcribing the DNA sequence into mRNA? In your own words, explain what this enzyme does.
Here is a eukaryotic gene. The numbers given are base pairs of exon and intron. How long in bases will the pre mRNA transcript be? Explain briefly. What is the maximum number of amino acids that could make up the protein product from the final mRNA? Explain briefly.
What happens when one base pair of DNA is lost from the coding region of a gene because of mutation? First explain how this would affect the mRNA sequence, and second, explain how this would alter the amino acid of the protein that is encoded.
When a eukaryotic gene is cut out of genomic DNA, geneticists have discovered that enabling the strands to hydrogen bond allows them to hybridize one of the gene's strands to the mRNA for that gene. How can you tell whether this gene undergoes alternative splicing by comparing the mRNAs that result?
Geneticists have found that when they cut out a eukaryotic gene from genomic DNA that they can hybridize one of the strands of that gene to the mRNA for that gene by allowing the strands to hydrogen bond. Why did the appearance of these hybridized strands provide evidence of the existence of introns in eukaryotic genes?
If the coding region of a gene (the exons) contains 2,100 base pairs of DNA, would a missense mutation causes a protein to be shorter, longer, or the same length as the normal 700 amino acid proteins? What would be the effect of a nonsense mutation? A sense mutation?
A certain gene in a bacterium codes for a polypeptide that is 400 amino acids long. How many nucleotides are needed in the mRNA to code for this polypeptide?
Refer to the DNA sequence provided:3’ -TACTGAAGCGGCAGCCCCGCATGAGTAGACCTTACT-5’ b. What is the amino acid sequence of the polypeptide chain that will be translated from the mRNAin (a)? (The question for A is this: What is the mRNA transcript of the anticoding strand of the DNA model?)
When scientists cut a eukaryotic gene from genomic DNA, they discovered that enabling the strands to hydrogen bond allows them to hybridize one of the gene's strands to the gene's mRNA. How can you tell whether this gene undergoes alternative splicing by comparing the various mRNAs that result?
The asterisk (*) in the diagram below indicates a single base mutation in the 5' splice site of the second intron of a eukaryotic gene. Due to this mutation, the second intron is now not ‘spliced out’ during the splicing process. What are the most likely consequences of this mutation with respect to the size of the pre-mRNA and the size of the mature mRNA? a. The pre-mRNA will be longer and the mature mRNA will be longer. b. The pre-mRNA will be longer and the size of the mature mRNA will not be affected c. The size of the pre-mRNA will not be affected and the mature mRNA will be longer d. The size of the pre-mRNA will not be affected and the size of the mature mRNA will not be affected