A man was brought to the hospital showing "pneumonia"-like symptoms.They took the viral load and determined this to be the new RNAretrovirus infecting lung cells. Since antibodies were unavailable, doctorsdecided to treat him with drugs. Which of the following would mostbenefit the patient?A. Drug A is an inhibitor of the binding of 4OS with 60S ribosome of the lungcells.B. Drug B is a structural analogue of the viral peptide that binds to the receptorof the host cell enabling viral entry into the cell.C. Drug C is a polar molecule that inhibits the lytic enzymes activated upon viralinfection.D. Drug D is an inducer of a proteolytic enzyme.E. Drug E is a steroid that binds at the regulatory site of a gene causing thesynthesis of a repressor that binds at the gene site for the receptor.

Retroviruses have special enzyme called as reverse transcriptase which translates its genetic…

Answered: A man was brought to the hospital…

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter17: Genes And The Immune System

Section: Chapter Questions

Problem 13QP: The Adaptive Immune Response Is a Specific Defense Against Infection In cystic fibrosis gene...

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Enveloped viruses, which have a membrane coat,gain access to the cytosol by fusing with a cell membrane.Why do you suppose that these viruses encode their ownspecial fusion protein, rather than making use of a cell'sSNAREs?
Some Covid 19 vaccines in development use the adenovirus, a common vector used in gene therapies, to inject the mRNa for the spike protein into human muscle cells. Why might vaccines using a virus vector be more likely to need only refrigeration and not deep-cold storage? Some older vaccines used a weakened strain of the pathogenic virus in the injection in the hope that the weakened virus would induce an immune response without causing disease. The virus vectors used in genetic engineering have all the harmful virus genes cut out and replaced with the foreign gene, such as one that makes a protein that is absent in the human patient. Which type of viral vaccine would you prefer to take as the safest option? Why?
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A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. It does this by inserting its genetic material (RNA) into the host cell and integrate its genetic material with the host genome. Explain in details how organisms eliminate the expression of viral genes? How this mechanism can prevent virus infections?
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Compare and contrast both the structure, AND the molecular mechanisms of the Moderna/Pfizer Covid-19 mRNA vaccines to the Johnson & Johnson adenovirus vaccine. Include in your answer a hypothesis as to why two doses of the mRNA vaccine are required, but only one does of the adenovirus vaccine is required.
The flow of genetic information is from DNA to RNA toprotein. In certain viruses, the flow of information is fromRNA to DNA. Does it appear possible for that informationflow to begin with proteins? Explain.
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Replication of both strands of DNA in adenoviruses occurs ina continuous (leading) fashion. How can this happen withoutviolating the rule that DNA synthesis always occurs in a5′ S 3′ direction?
Many viruses that infect eukaryotic cells express genes that alterthe regulation of host gene expression to promote viral replication.For example, herpes simplex virus-1 (HSV-1) expresses aprotein called ICP0, which is necessary for successful viral infectionand replication within the host. Lutz et al. (2017. Viruses9: 210) showed that ICP0 can act as a ubiquitin ligase and targetthe redundant transcriptional repressors ZEB1 and ZEB2,which leads to upregulation of the miR-183 cluster (a set of threemiRNAs transcribed from the same locus). Speculate on how miR-183 cluster upregulation may benefitthe virus.
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What should be the environmental conditions for the fusion proteins of the influenza virus to show activity? Write. Based on this, what advice can you give people to protect against this virus? explain

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