A new class of cholesterol-lowering treatments that utilize small interfering RNAs (siRNAs) are currently in clinical trials. These work by binding to and degrading specific mRNAs that encode apolipoproteins (O'Donoghue et al., 2022). Which specific cells do these siRNAs have to be directed to in order to be effective? O adipose cells O hepatocytes macrophages pancreatic beta cells

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter32: The Reception And Transmission Of Extracellular Information
Section: Chapter Questions
Problem 21P
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new class of cholesterol-lowering treatments that utilize small interfering RNAs (siRNAs) are
currently in clinical trials. These work by binding to and degrading specific mRNAs that encode
apolipoproteins (O'Donoghue et al., 2022). Which specific cells do these siRNAs have to be
directed to in order to be effective?
O adipose cells
O hepatocytes
macrophages
pancreatic beta cells
Transcribed Image Text:new class of cholesterol-lowering treatments that utilize small interfering RNAs (siRNAs) are currently in clinical trials. These work by binding to and degrading specific mRNAs that encode apolipoproteins (O'Donoghue et al., 2022). Which specific cells do these siRNAs have to be directed to in order to be effective? O adipose cells O hepatocytes macrophages pancreatic beta cells
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