(a) Nucleotide excision repair (b) Photoreactivation (c) Base excision repair (d) Recombinational repair (e) SOS-driven error-prone repair (f) Alkyltransferase repair (g) Mismatch repair (h) Double-strand break repair II 1. RecA protein participates. 2. Damaged nucleotides are removed by nick translation. 3. A free radical mechanism is involved. 4. The repair enzyme functions only once. 5. The key enzyme contains a bound folate cofactor. 6. No bases or nucleotides are removed from the DNA. 7. Deficiency of this enzyme in humans greatly increases the risk of skin cancer. 8. This system is chiefly responsible for the mutagenic effect of ultraviolet light. 9. This process begins with cleavage of two phosphodiester bonds. 10. This process begins up to 1 kbp away from the site to be repaired. 11. DNA ligase catalyzes the final reaction. 12. This process also occurs in meiotic recombination. 13. Replication fork regression might occur during this process.

(a) Nucleotide excision repair (b) Photoreactivation (c) Base excision repair (d) Recombinational repair (e) SOS-driven error-prone repair (f) Alkyltransferase repair (g) Mismatch repair (h) Double-strand break repair II 1. RecA protein participates. 2. Damaged nucleotides are removed by nick translation. 3. A free radical mechanism is involved. 4. The repair enzyme functions only once. 5. The key enzyme contains a bound folate cofactor. 6. No bases or nucleotides are removed from the DNA. 7. Deficiency of this enzyme in humans greatly increases the risk of skin cancer. 8. This system is chiefly responsible for the mutagenic effect of ultraviolet light. 9. This process begins with cleavage of two phosphodiester bonds. 10. This process begins up to 1 kbp away from the site to be repaired. 11. DNA ligase catalyzes the final reaction. 12. This process also occurs in meiotic recombination. 13. Replication fork regression might occur during this process.

Biology: The Dynamic Science (MindTap Course List)

4th Edition

ISBN:9781305389892

Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Chapter19: Genomes And Proteomes

Section: Chapter Questions

Problem 12TYK

See similar textbooks

Similar questions

DNA repair enzymes preferentially repair mis- matched bases on the newly synthesized DNA strand, using the old DNA strand as a template. If mismatches were instead repaired without regard for which strand served as template, would mismatch repair reduce repli- cation errors? Would such a mismatch repair system result in fewer mutations, more mutations, or the same number of mutations as there would have been without any repair at all? Explain your answers.
Contrast the various types of DNA repair mechanisms known to counteract the effects of UV radiation. What is the role of visible light in repairing UV-induced mutations?
Consider the following sequence of DNA: 3'-TTA CGG-5'What dipeptide is formed from this DNA after transcription and translation? b. If a mutation converts CGG to CGT in DNA, what dipeptide is formed? c. If a mutation converts CGG to CCG in DNA, what dipeptide is formed? d. If a mutation converts CGG to AGG in DNA, what dipeptide is formed?
2b) Suppose you generated a mutant E. coli strain in which it was DNA Polymerase I that was inactivated - assuming that all the other enzymes involved in replication remained fully functional, how would DNA replication in these mutant cells lacking DNA Pol I differ from DNA replication in normal E. coli? Briefly explain why you would expect to see that change/those changes in DNA replication in the mutant cells.
Given the following DNA sequence: 5’-ATGCGGCCAAGGTCAGAGTGACA-3’ a) If this DNA strand represents the “Sense Strand” of DNA, what would be the RNA sequence? b) If this DNA strand represents the “Antisense Strand” of DNA, what would be the RNA Sequence? c) What would be the other strand of DNA?
. Which of the following statements best describe the mismatch repair pathway?a. It is part of the 3′to 5′proofreading function of DNApolymerase.b. It acts after DNA replication by recognizing mismatched base pairs.c. It is activated by stalled replication forks.d. It is coupled to transcription.
For each DNA repair process in column I, list all characteristics fromcolumn II that correctly describe that process.I(a) Nucleotide excision repair(b) Photoreactivation(c) Base excision repair(d) Recombinational repair(e) SOS-driven error-prone repair(f) Alkyltransferase repair(g) Mismatch repair(h) Double-strand break repairII1. RecA protein participates.2. Damaged nucleotides are removed by nick translation.3. A free radical mechanism is involved.4. The repair enzyme functions only once.5. The key enzyme contains a bound folate cofactor.6. No bases or nucleotides are removed from the DNA.7. Deficiency of this enzyme in humans greatly increases the risk of skincancer.8. This system is chiefly responsible for the mutagenic effect of ultravioletlight.9. This process begins with cleavage of two phosphodiester bonds.10. This process begins up to 1 kbp away from the site to be repaired.11. DNA ligase catalyzes the final reaction.12. This process also occurs in meiotic recombination.13.…
Who experimentally prove that DNA replication is semi conservative?
What is meant by non-classical DNA-dependent DNA polymerases? What roles do they play in our cells?
5’ TAAGCGTAACCCGCTAA CGTATGCGAAC GGGTCCTATTAACGCAC 3’ 3’ ATTCGCATTGGGCGATT GCATACGCTTG CCCAGGATAATTGCGTG 5’ Imagine that the double-stranded DNA molecule shown above was broken at the sites indicated by spaces in the sequence and that before the breaks were repaired the DNA fragment between the breaks was reversed. What would be the base sequence of the repaired molecule? Show the sequence, label the 5’ and 3’ ends and briefly explain the reasoning supporting your answer
Please explain one type of “DNA repair” mechanism (what is it, when is it used, how does it work).
In some organisms, UV-induced thymine dimers can be repaired by photoreactivation, in which energy from visible light is used to split the bonds forming the cyclobutane ring ? true or false Non-homologous end joining occurs when enzymes cut out a few nucleotides around a double strand DNA break, and then fuse the ends back together (right) true or false?