A2 A particular enzyme's activity is low at high pH butincreases at lower pH. These data suggest that forefficient catalysis to occur, a functional group on theenzyme or on the substrate must be,protonatedreducedⒸexidizedOdenatureddeprotonatedIn the Lineweaver-Burke plot below, which kineticparameter(s) change upon addition of the non-competitive inhibitor?Noncompetitiveinhibitor1/VDNo inhibitorpresentD1/[5]ⒸVⒸKMBoth andNeither V An plot of the activity of an allosteric enzyme(velocity (V) versus substrate concentration [S]) has asigmoidal shape. How will the addition of an activatorof this enzyme change its kinetic activity data?The curve will shift to the rightThe curve will shift to the left.The curve will become more sigmoidal, so that the firsthalf is decreased and the second half increasedThe curve will be more hyperbolicThere will be no effectWhich of the following amino acids have side chainsthat fit into the S1 pocket of chymotrypsin?PheArgAspLysAla

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A particular enzyme's activity is low at high pH but increases at lower pH. These data suggest that for efficient catalysis to occur, a functional group on the enzyme or on the substrate must be, protonated O reduced exidized Odenatured deprotonated

A particular enzyme's activity is low at high pH but increases at lower pH. These data suggest that for efficient catalysis to occur, a functional group on the enzyme or on the substrate must be, protonated O reduced exidized Odenatured deprotonated

Chemistry for Today: General, Organic, and Biochemistry

9th Edition

ISBN:9781305960060

Author:Spencer L. Seager, Michael R. Slabaugh, Maren S. Hansen

Publisher:Spencer L. Seager, Michael R. Slabaugh, Maren S. Hansen

Chapter20: Enzymes

Section: Chapter Questions

Problem 20.75E: In the multienzyme sequence shown below, molecules of D are able to fit to the enzyme E1 and prevent...

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Concept explainers

Vitamins and Coenzymes

A class of organic compounds needed in the human body for normal activities is known as vitamins. They are characterized into two parts depending upon their solubility in water. They can act as coenzymes, cofactors, or prosthetic groups for enzymes.

Question

A particular enzyme's activity is low at high pH but
increases at lower pH. These data suggest that for
efficient catalysis to occur, a functional group on the
enzyme or on the substrate must be,
protonated
reduced
Ⓒexidized
Odenatured
deprotonated
In the Lineweaver-Burke plot below, which kinetic
parameter(s) change upon addition of the non-
competitive inhibitor?
Noncompetitive
inhibitor
1/V
D
No inhibitor
present
D
1/[5]
ⒸV
ⒸKM
Both and
Neither V

An plot of the activity of an allosteric enzyme
(velocity (V) versus substrate concentration [S]) has a
sigmoidal shape. How will the addition of an activator
of this enzyme change its kinetic activity data?
The curve will shift to the right
The curve will shift to the left.
The curve will become more sigmoidal, so that the first
half is decreased and the second half increased
The curve will be more hyperbolic
There will be no effect
Which of the following amino acids have side chains
that fit into the S1 pocket of chymotrypsin?
Phe
Arg
Asp
Lys
Ala

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