A patient has a defective liver FBPase-2 enzyme, the enzyme that converts F2,6P into F6P. This enzyme is inactive. What effect would this have on the differential regulation of glycolysis and gluconeogenesis in liver cells? How would this affect a person’s ability to respond appropriately to a low blood sugar state? What about a high blood sugar state?

A patient has a defective liver FBPase-2 enzyme, the enzyme that converts F2,6P into F6P. This enzyme is inactive. What effect would this have on the differential regulation of glycolysis and gluconeogenesis in liver cells? How would this affect a person’s ability to respond appropriately to a low blood sugar state? What about a high blood sugar state?

Basic Clinical Laboratory Techniques 6E

6th Edition

ISBN:9781133893943

Author:ESTRIDGE

Publisher:ESTRIDGE

Chapter6: Basic Clinical Chemistry

Section6.5: Blood Glucose And Hemoglobin A1c

Problem 14RQ

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An individual has a genetic deficiency that prevents the production of glucokinase. Following a carbohydrate meal, do you expect blood glucose levels to be high, low, or about normal? What organ accumulates glycogen under these circumstances?
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