A person consumes 100 μg of a tracer chemical. Assume that the person is able to collect all of the tracer in their urine (and therefore measure the amount that has come out of the body), as well as the concentration in the blood, as a function of time (see table). (a) Is a first-order rate constant appropriate for describing the process of elimination via the kidneys? Justify your answer. (b) Assuming that the answer to a is “yes,” find the rate constant k and the total volume V from these data.
A person consumes 100 μg of a tracer chemical. Assume that the person is able to collect all of the tracer in their urine (and therefore measure the amount that has come out of the body), as well as the concentration in the blood, as a function of time (see table). (a) Is a first-order rate constant appropriate for describing the process of elimination via the kidneys? Justify your answer. (b) Assuming that the answer to a is “yes,” find the rate constant k and the total volume V from these data.
Chapter19: Calculating Iv Infusion And Completion Times
Section: Chapter Questions
Problem 20SST
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A person consumes 100 μg of a tracer chemical. Assume that the person is able to collect all of the tracer in their urine (and therefore measure the amount that has come out of the body), as well as the concentration in the blood, as a function of time (see table).
(a) Is a first-order rate constant appropriate for describing
the process of elimination via the kidneys? Justify your answer.
(b) Assuming that the answer to a is “yes,” find the rate constant k and the total volume V from these data.
Transcribed Image Text:Amount collected in
urine during the
previous hour (µg)
Concentration in the
Time (h)
blood (µg/L)
1
9.4
90
2
8.7
82
3
7.9
75
4
6.9
66
6.5
61
5.7
55
5
50
8
4.9
43
4.3
39
10
3.9
35
67
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