08:24 Tue Nov 2390%T+ :E) 10.05. A protease binds its substrate in an extended conformation for better access to its amidelinkages for hydrolysis. When this happened, which quadrant of a Ramachandran plot will thesubstrate's phi-psi bonds most likely be located in?18012060-60-120-180-1801806 (dearees)A) Southwest quadrant where y = negative and O =B) Southeast quadrant where y = negative and 0 = positiveC) Northwest quadrant where = positive and 0 = negativeD) Northeast quadrant where y = positive and O = positiveE) In the center where O = ) =0°negative%3D%3D3%3D226. Secondary structure is largely stabilized by hydrogen bonds ; tertiary structure is largely stabilizedby the hydropnobic etlect. (WRITE your answer for BOTH blanks into the blanks above or in orderon your answer sheet. Both must be correct for credit.)>ý (degrees)

For better access of amide linkage the conformation of protease will be antiparallel beta sheet.

Answered: A protease binds its substrate in an…

Biochemistry

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Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter19: The Tricarboxylic Acid Cycle

Section: Chapter Questions

Problem 23P

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A protease binds its substrate in an extended conformation for better access to its amide linkages for hydrolysis. When this happened, which quadrant of a Ramachandran plot will the substrate's phi-psi bonds most likely be located in?