is the type of enzyme specificity exhibited by hydrolysis of urea using urease
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A: During polypeptide synthesis the amino acids are joined together by peptide bond and the peptide…
Q: what is the relationship of enzyme and substrate type
A: Enzymes are also known as biological catalysts.
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Q: true of false question. the formation of the acyl-enzyme is indicative of covalent catalysis.
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A: Introduction: Gluconeogenesis is the synthesis of glucose from non-carbohydrate compounds and mainly…
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A: For better access of amide linkage the conformation of protease will be antiparallel beta sheet.
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Q: Which of the following amino acid residues would not participate in general acid-base catalysis? A.…
A: Acid-base catalysis is the reaction mechanism that deals with the transfer of a proton from one…
Q: Explain Maple syrup urine disease . which enzyme is deficient in it ?
A: Maple syrup urine disease is a rare genetic disorder which is characterized by the deficiency of an…
Q: what are the advantages of immobilized enzymes over free enzymes.
A: Immobilized enzymes, as the name suggests these are the enzymes that are not movable or restricted…
Q: The following enzymes belong to the same class of enzymes, except for A. Chymotrypsin B. Thrombin C.…
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Q: dipeptide + H2O → 2 amino acids An enzyme that catalyzes the reaction above would be called a a.…
A: Enzymes are the protein molecule, which helps in the catalysis of the chemical reaction.
Q: Which of the following is true about urease being a hydrolase enzyme? A. It catalyzes the…
A: Since you have asked multiple question, we will solve the first question for you. If you want any…
Q: What type of linkage is catalyzed by peptidyl transferase activity? a. anhydride b. mixed anhydride…
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Q: E. coli can convert glutamate to ornithine. Describe the two reactions that do so.
A: In E.coli, the ornithine compound is synthesized from the compound glutamate.
Q: Identification of the active site of an enzyme: 2.2 The use of substrate analogues
A: Introduction Enzymes are the biomolecules especially proteins. Which helps in the speeding up of…
Q: In considering the rate of reaction for urea conversion, the enzyme is______, the substrate is______…
A: The rate of reaction can be defined as the speed at which reactants are changed into products. For…
Q: Urea synthesis begins with the formation of _____________.
A: The urea cycle is a biochemical process that converts the toxic substance (ammonia) which was…
Q: Enzyme modification by chemical procedures affecting amino acid side chains
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Q: Which of the following amino acid residues cannot play a role in acid-base catalysis? a. Aspartate…
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Q: GLUCONEOGENESIS Reactant Coenzyme/ Product Cofactor Enzymes
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A: Urea-cycle disorder is a genetic disorder that affects the breakdown of proteins in the body. The…
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Q: List three proteases and their substrates.
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A: The question asks to determine the fill up type:In considering the rate of reaction for urea…
Q: Urea is a metabolic by-product of the catabolism of _____________.
A: Urea is the nitrogenous waste secreted by mammals. It consists of 2 amine groups bonded to a…
Q: In considering the rate of reaction for urea conversion, the enzyme is _____ , the substrate is…
A: The rate of reaction- it is defined as the pace at which reactants are changed into products. For…
Q: What is Hunter's disease? Which enzyme is deficient in this disease.
A: Mucopolysaccharidosis is also known as lysosomal storage disease in which mucopolysaccharides…
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Q: Increasing the UREA concentration 2. Increasing the UREASE concentration 3. Increasing the…
A: Urease is liver enzyme which convert urea to carbon dioxide and ammonia. It is nickel containing…
Q: The class of the enzyme catalyzing the reaction shown in this figure is a(n) Choose the one best…
A: Given, that the enzyme can catalyse the conversion of glucose to glucose-6-phosphate by transferring…
Q: Define the following terms:a. oxidoreductaseb. lyasec. ligased. transferasee. hydrolasef. isomerase
A: These all that are mentioned or asked in the question are Enzymes. we can also identify it by just…
Q: The immediate donors of the nitrogen atoms of urea are: a. Aspartate and glutamate b. Glutamate and…
A: Urea cycle is a cyclic pathway related to the synthesis of urea, one nitrogen is derived from free…
Q: What classification of enzyme is catalase? Give the Enzyme Commission (E.C.) number of catalase.
A: Enzymes are biocatalysts that increase the rate of the chemical reaction without undergoing any…
Q: Cite one condition/illness arising from the absence or lack of a certain enzyme.
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Q: Name the enzyme whose substrate is(a) Urea (b) Cellulose
A: Introduction: Enzymes are proteins that catalyze the reaction. Their main function is to accelerate…
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- Which of the following statements regarding enzymes and transition states is true? stabilization of the transition state must be less than stabilization of ES for catalysis to occur binding of substrate to an enzyme often causes strain, thus promoting transition state formation the transition state conformation of an enzyme catalyzed reaction is identical to the conformation seen in the uncatalyzed transition state formation of the transition state always assures that the reaction will proceed to product none of the above are trueOne way of expressing the rate at which an enzyme can catalyze a reaction is to state its turnover number. The turnover number is the maximum number of substrate molecules that can be acted on by one molecule of enzyme per unit of time. The table gives the turnover number of four representative enzymes. Enzyme Substrate Turnover number (per second) Ribonuclease RNA 100 Fumarase fumarate 800 Lactate dehydrogenase lactate 1000 Urease urea 10,000 How many molecules of urea can one molecule of urease act on in 12.0 min ?Which of the following statements about enzyme character-istics is true?(a) Enzymes generally exhibit a high degree of specificityfor one particular substrate.(b) Enzyme-substrate complexes occur when a substratemolecule collides with the allosteric site of an enzyme.(c) Chemical bonds within a substrate are strength-ened when this substrate forms an enzyme-substratecomplex.(d) Enzymes have a region called the active site, which pro-vides an area where it can form a loose association withits substrate.(e) a and d.
- Carbonic anhydrase is strongly inhibited by the drug acetazolamide, which is used as a diuretic (i.e., to increase the production of urine) and to lower excessively high pressure in the eye (due to accumulation of intraocular fluid) in glaucoma. Carbonic anhydrase plays an important role in these and other secretory processes because it participates in regulatingthe pH and bicarbonate content of several body fluids. The experimental curve of initial reaction velocity (as percentage of Vmax ) versus [S] for the carbonic anhydrase reaction is illustrated below (upper curve). When the experiment is repeated in the presence of acetazolamide, the lower curve is obtained. From an inspection of the curves and your knowledge of the kinetic properties of competitive and mixed enzyme inhibitors, determinethe nature of the inhibition by acetazolamide. Explain your reasoning.The active (catalytic) site of an enzyme contains the side chains of amino acid residues that areconserved because they participate in the protein’s catalytic activity. The bulk of the enzyme,however, is not part of the active site. A substantial amount of energy is required to synthesizeenzymes. Why are these molecules so large?Some metabolic conditions such as diabetesmellitus cause disturbances in the acid–basebalance of the body, which gives the bodyfluids an abnormally low pH. Explain howthis could affect enzyme–substrate reactionsand metabolic pathways in the body.
- What are the description of the ff?A. Effect of pH with enzymaticactivity. Include example ofenzymes optimum pH.B. Effect of activators on theactivity of enzymes. Includeexamples.Protease is an enzyme that catalyzes the breaking of amide bonds which is very stable at “mild” conditions, namely body temperature and pH 7 (if done in the lab requires hot conditions, concentrated HCl for hours). Some proteases have two aspartic acid residues at their active sites. Write the reaction mechanism (which follows general acid-base catalysis)Which of the following is not true about enzymes? 4. Transition state stabilization can significantly increase the activation energy for a reaction. Nucleophilic groups can catalyze reactions through the transient formation of covalent bonds with the substrate. Zymogens are the inactive precursors of enzyme. Enzymes typically act under milder conditions of temperature and pH than non-enzyme chemical catalysts. Enzyme inhibitors interact reversibly or irreversibly with an enzyme to alter its Km and /or Vmax values.
- Which of the following statements are correct? explain your answers.a. The active site of an enzyme usually occupies only a small fraction of the enzyme surface.B. catalysis by some enzymes involves the formation of a covalent bond between an amino acid side chain and a substrate molecule.c. a β sheet can contain up to five strands, but no more.d. The specificity of an antibody molecule is contained exclusively in loops on the surface of the folded light-chain domain.e. The possible linear arrangements of amino acids are so vast that new proteins almost never evolve by alteration of old ones. f. allosteric enzymes have two or more binding sites. G. noncovalent bonds are too weak to influence the three- dimensional structure of macromolecules.In _____________ inhibition, the EI complex readily dissociates and the enzyme is again available for substrate binding.Ethylene glycol (HO−CH2−CH2−OH) is a major component of antifreeze. In the body, it is first converted to HOOC−CHO (oxoethanoic acid) and then to HOOC−COOH (oxalic acid), which is toxic. What class of enzyme catalyzes both of the reactions of ethylene glycol? The treatment for the ingestion of ethylene glycol is an intravenous solution of ethanol. How might this help prevent toxic levels of oxalic acid in the body?