A rare class of dominant gain-of-function _______ arisesfrom neomorphic mutations that generate a novel phenotype.?

Q: Why most loss-of-function mutant alleles are recessive to wild-type alleles

A: The loss-of-function mutations are also known as inactivating mutations that result in the gene…

Q: A geneticist discovers a male mouse with greatly enlarged testes in his laboratory colony. He…

A: Introduction As we know the testes are present in males only so enlargement of testes in male mouse…

Q: Does this statement is a  example of a phenocopy? Explain your reasoning. Q. Phenylketonuria results…

A: Phenylketonuria is a genetic disorder characterized by the deficiency or absence of the enzyme…

Q: Recessive Lethal Mutations in Diploids Can Be Identified by _______ and Maintained in ___________.

A: Lethal alleles are those which cause the death of an organism that carries them. It results from…

Q: Loss of function mutation results in a _ allele.

A: Mutations are sudden changes in the gene sequence. When these changes causes loss of function of an…

Q: If children obtain half of their Gene's from one parent and half from the other parent, why aren't…

A: A genome of offspring is inherited from both the parents. Half of the genetic material is inherited…

Q: Thomas discovered a devastating piece of family historywhen he learned that his brother had been…

A: Sir Gregor Mendel was a priest and a teacher who did the famous hybridization experiment on garden…

Q: Why mitochondrial DNA is inherited from mother only in contrast with nuclear DNA which inherited…

A: DNA is the genetic material in most living organisms. It is the information hub of the cell that…

Q: A 30 - year - old woman was undergoing therapy for b-thalassemia,a recessive trait caused by absence…

A: Bone marrow or HSC (hematopoietic stem cells) transplantation is a procedure during which healthy…

Q: Why The Same Genotype Does Not Always Produce the Same Phenotype?

A: Genotype is the gene complement or the genetic constitution of an individual with regard to the…

Q: A particular disease is found in a group of South AmericanIndians. During the 1920s, many of these…

A: Any abnormal condition which affects the functions or structure of either the whole body or some…

Q: The differential expression of alleles depending on whether they are maternally or paternally…

A: The correct option is option (D) i.e, Genomic Imprinting. Explaination: Genomic imprinting is the…

Q: Janet and her family members have attached earlobes (recessive trait). However, her maternal…

A: According to the Mendelian inheritance the phenotype of an organism is controlled by the genes that…

Q: Why do gene mutations not result in chromosomal mutations?

A: Answer: Introduction: Mutation- These are the random heritable changes that occurs in the DNA…

Q: In chickens, a dominant hereditary abnormality homozygous (CC). The recessive condition Another gene…

A: In this given traits one is completely dominant over other in case of skin colour, that is…

Q: How mutations and the resulting alleles affect an organism’s phenotype ?

A: By changing a gene's directions for making a protein, a transformation can make the protein…

Q: .In humans, how does the inheritance of sex-linked traits differ from autosomal traits?

A: A genetically defined trait is one that is inherited. Mendelian genetics dictates that inherited…

Q: Which of the following are associated with dynamic mutations? O Genomic imprinting O Trinucleotide…

A: First of all we will discuss that, what is dynamic mutation and its causes.  Dynamic mutation is the…

Q: In retinoblastoma, a mutation in one allele of the RB1 tumorsuppressorgene can be inherited from the…

A: Retinoblastoma is a rare retinal disease that develops a malignant tumor in the retinal layers of…

Q: Traits are inherited germ line wise (vertical inheritance) and somatic (epigenetics) inheritance,…

A: Inheritance or heredity refers to the transfer of traits or characters from parents to subsequent…

Q: Why a loss or an excess in genetic material leads to the expression of an abnormal phenotype

A: The translocation happens when a piece of one chromosome is servers and connects to another…

Q: Autosomal Recessive Inheritance (trait only expressed if homozygous recessive)An albino man (nn)…

A: Autosomal recessive trait only gets expressed when they are present in homozygous recessive…

Q: A rare dominant mutation expressed at birth was studiedin humans. Records showed that six cases were…

A: Answer : Since 2 cases were the ones which already had the mutation already present in their…

Q: A mutation on an autosome causes a particular protein to be overproduced, and the excess protein…

A: Mutations are random changes in the genome.

Q: • Deletions remove _______________from a chromosome and causemutant phenotypes mainly through…

A: Mutation is defined as a change which occurs in the sequence of DNA molecule which is due to…

Q: Albinism is an autosomal recessive disorder. If a non-carrier normal male mates with an albino…

A: Given: Albinism is an autosomal recessive disorder. Let, Normal person (not having albino) - AA…

Q: There are six types of agglutinogen named C,D, E and c,d,e.the first three are dominant and last…

A: In blood typing, antigens on the surfaces of red blood cells (RBCs) are known as agglutinogens.…

Q: The maternal-effect mutation bicoid (bcd) is recessive. Inthe absence of the bicoid protein product,…

A: Introduction: Bicoid (Bcd) protein is a product of the bicoid gene having a maternal effect and is…

Q: Each of us is genetically unique. Describe two processes that ensure that your future full sibling…

A: DNA is the genetic material present in most of the living organisms. The DNA is made up of 4…

Q: Maternal influence is considered a transient inheritance, explain?

A: Inheritance in genetics is referred to as a phenomenon which involves the transfer of genetic…

Q: CdLS is usually caused by new mutation in oneparent’s gamete. Why?

A: The changes in the sequence of nucleotides are called mutations. The agents that cause mutations are…

Q: If the effects of mutations 1 + 3 is an eye size intermediate between wild type and mutation 1…

A: In biology, a mutation is an alteration in the nucleotide sequence of the genome of an organism,…

Q: Suppose a maternal effect gene exists as a functional dominantallele and a nonfunctional recessive…

A: A dominant allele is the one which expresses itself in its homozygous as well as in heterozygous…

Q: A modification of a gene or chromosome that occurs during gamete formation or early development that…

A: There are many inheritance patterns that violate the law of segregation given by Gregor Mendel. Some…

Q: Null mutations are valuable genetic resources becausethey allow a researcher to determine what…

A: Null mutation is a type of mutation in which a copy of gene becomes non-functional. This type of…

Q: Examples of genomic imprinting other than insulin-like growth factor 2

A: Genetic imprinting can be defined as when one copy of a gene is silenced due to its parental origin.…

Q: The maternal-effect mutation bicoid (bcd) is recessive. Inthe absence of the bicoid protein product,…

A: A homozygous male (bcd⁻/bcd⁻) child is possible only when the mother is heterozygous (bcd⁺/bcd⁻) and…

Q: Among mammals, measurements of the rate of generation of autosomal recessive mutations have been…

A: Scientists analyze mutations in model organisms such as mice, to understand the molecular basis of…

Q: Albinism occurs when cells cannot chemically synthesize pigment molecules. This occurs because the…

A: Albinism is a category of genetic illnesses in which the pigment melanin, which affects the colour…

Q: A 30 - year - old woman was undergoing therapy for b-thalassemia,a recessive trait caused by absence…

A: Introduction: Beta thalassemia is an autosomal recessive inherited from abnormal genes of parent. In…

Q: Galton’s traits are readily observed in everyday life. What did Galton discover?

A: Mendel proposed the laws of inheritance based on his results of the hybridization experiments

Q: Transmission of information from cells to cell or from parent to progeny that is not encoded in DNA.…

A: The DNA or deoxyribonucleic acid contain the genetic information that is transmitted from parents to…

Q: Why mutation behaves as a recessive lethal allele ?

A: Mutation can be outlined as the change within our DNA sequence and it results from the copying…

Q: Whar is the probable pattern of inheritance and why

A: The pattern of inheritance is the manner in which a genetic trait or disorder is passed from one…

Q: What is mutation? Distinguish between (i) neutral and silent mutation (ii) germ line and somatic…

A: Mutations can sometimes be beneficial, when they result in traits that will benefit the organism.…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.