A particular disease is found in a group of South AmericanIndians. During the 1920s, many of these people migrated toCentral America. In the Central American group, the diseaseis never found. Discuss whether or not you think the diseasehas a genetic component. What types of further observationswould you make?

A particular disease is found in a group of South AmericanIndians. During the 1920s, many of these people migrated toCentral America. In the Central American group, the diseaseis never found. Discuss whether or not you think the diseasehas a genetic component. What types of further observationswould you make?

Name: A particular disease is found in a group of South AmericanIndians. Dur
Uploaded: 2024-03-20T06:42:55.000Z
Channel: Bartleby
Description: A particular disease is found in a group of South AmericanIndians. During the 1920s, many of these people migrated toCentral America. In the Central American group, the diseaseis never found. Discuss whether or not you think the diseasehas a genetic

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter6: Cytogenetics: Karyotypes And Chromosome Aberrations

Section: Chapter Questions

Problem 13QP: As a physician, you deliver a baby with protruding heels and clenched fists with the second and...

See similar textbooks

Similar questions

Why is knowing the genetic basis of a trait such as blond hair important? Why would scientists go to the trouble to investigate the genetic basis of blond hair in Solomon Islanders?
Familial retinoblastoma, a rare autosomal dominant defect, arose in a large family that had no prior history of the disease. Consider the following pedigree (the darkly colored symbols represent affected individuals): a. Circle the individual(s) in which the mutation most likely occurred. b. Is the person who is the source of the mutation affected by retinoblastoma? Justify your answer. c. Assuming that the mutant allele is fully penetrant, what is the chance that an affected individual will have an affected child?
Which members of the pedigree could have been carriers, and which might have been the source of the mutation?
As a physician, you deliver a baby with protruding heels and clenched fists with the second and fifth fingers over-lapping the third and fourth fingers. a. What genetic disorder do you suspect the baby has? b. How do you confirm your suspicion?
A researcher sequences the whole exome of a patientsuffering from Usher syndrome, a rare autosomal recessive condition that is nonetheless the leading causefor simultaneous deafness and blindness. The exomesequence does not show homozygosity for any polymorphisms different from the human RefSeq.a. How could the researcher examine the data alreadygathered to try to find the disease gene, assumingthe sequence is accurate?b. If the attempt described in part (a) was unsuccessful, the researcher might contemplate sequencingthe patient’s whole genome. What are the potentialpitfalls of this strategy?
Bloom syndrome is an autosomal recessive disease that exhibitshaploinsufficiency. A recent survey showed that people heterozygousfor mutations at the BLM locus are at increased risk of colon cancer.Suppose you are a genetic counselor. A young woman is referred to youwhose mother has Bloom syndrome; the young woman’s father has nofamily history of Bloom syndrome. The young woman asks whether sheis likely to experience any other health problems associated with herfamily history of Bloom syndrome. What advice would you give her?
What genetic model of an organism is the most ideal? And why is it an ideal model in genetics?
As a genetic counselor, you may face some ethical dilemmas.Imagine that a couple came to your office to discuss potential color blindness in their children.The man is not color blind, but his wife is. They already have one daughter that is color blindand want to know the probability of future children having the disorder. First, you will need toexplain to the couple the difference between sex chromosomes and autosomal chromosomes andthat color blindness is caused by a recessive mutation in a gene found on the X chromosome.Once they understand this, you can then explain to them the probability of other offspring havingthe disorder. What is the dilemma in this case and why might you need to suggest to the couplethat they see a marriage counselor
. If you were a genetic counselor and had a patient withMERRF who wanted to have a child, what kind of advice could you give about the chances the child wouldalso have the disease? Are there any tests you couldsuggest that could be performed prenatally to determine if a fetus would be affected by MERRF?
DNA sequencing of your own two β-globin genes (one from each of your two Chromosome 11s) reveals a mutation in one of the genes. given this information alone, should you worry about being a carrier of an inherited disease that could be passed on to your children? What other information would you like to have to assess your risk?
Explain, at the molecular level, why human genetic diseases oftenfollow a simple Mendelian pattern of inheritance, whereas mostnormal traits, such as the shape of your nose or the size of yourhead, are governed by multiple gene interactions.
Ehler-Danlos syndrome is a rare disorder caused by a mutation ina gene that encodes a protein called collagen (type 3 A1). Collagenis found in the extracellular matrix that plays an important role inthe formation of skin, joints, and other connective tissues. Peoplewith Ehler-Danlos syndrome have extraordinarily flexible skin and very loose joints. The pedigree below contains several individualsaffected with this syndrome, shown with black symbols. Based onthis pedigree, does the syndrome appear to follow autosomalrecessive, autosomal dominant, X-linked recessive, or X-linkeddominant inheritance? Explain your reasoning.