A researcher is testing the effectiveness of an intervention for patients with type 2 diabetes and depression that focuses on increasing medication adherence compared with usual primary care. Patients randomized to the intervention group were more likely to achieve remission of depressio compared with patients in the usual care group at 12 weeks (intervention 58.7% vs usual care 30.7%, p <.001). Based on this information and the information found in table 1, how would you interpret the study findings. Table 1. Baseline Characteristics of Study Population Characteristic Sociodemographic Usual Care (n=88) Intervention (n=92) P value
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- An article from the American Journal of Public Health reports the results from a randomized study designed to evaluate the efficacy of an intervention targeted to Hispanic/Latino men who identify as gay, bi-sexual or other men who have sex with men (MSM). A representative sample of 254 such men was randomized to be in either the intervention group (n=152, with 141 ultimately participating in the study) or the control group (n=152, with 147 ulitmately participating in the study). The primary outcome under study getting tested for HIV within the six-months following group assignment (randomization) among those who had been sexually active in this same six-month follow-up period. At six months of follow-up, 141 subjects in the intervention group reported having had sex (with men and/or women) since randomization. Of these 141 men, 114 had been tested for HIV since being randomized. At six months of follow-up, 147 subjects in the control group reported having had sex (with men…Landolt et al. (A-26) examined rates of posttraumatic stress disorder (PTSD) in mothers and fathers. Parents were interviewed 5 to 6 weeks after an accident or a new diagnosis of cancer or diabetes mellitus type I for their child. Twenty-eight of the 175 fathers interviewed and 43 of the 180 mothers interviewed met the criteria for current PTSD. Is there sufficient evidence for us to conclude that fathers are less likely to develop PTSD than mothers when a child is traumatized by an accident, cancer diagnosis, or diabetes diagnosis? Let alpha = 0.05In a randomized double-blind clinical trials of a new vaccine children were randomly divided into two groups subjects in group one received the new vaccine while subjects in group 2 received a control vaccine after the second dose 112 of 690 subjects in the experimental group 1 experienced drowsiness as a side effect after the second dose 69 of 571 of the subjects in the control group 2 experienced drowsiness as a side effect does the evidence suggest that a higher proportion of subjects in group 1 experience drowsiness as a side effect than subjects in group 2 at 0.05 level of significance? Determine the null and alternative hypothesis? find the test statistic for this hypothesis test? determine the P value for this hypothesis test? do we reject or not reject the null hypothesis and why? State your conclusion?
- In randomized, double-blind clinical trials of a new vaccine, infants were randomly divided into two groups. Subjects in group 1 received the new vaccine while subjects in group 2 received a control vaccine. After the second dose, 126 of 387 subjects in the experimental group (group 1) experienced drowsiness as a side effect. After the second dose, 158 of 574 of the subjects in the control group (group 2) experienced drowsiness as a side effect. Does the evidence suggest that a higher proportion of subjects in group 1 experienced drowsiness as a side effect than subjects in group 2 at the α=0.01 level of significance? Verify the model requirements. Select all that apply. A. The sample size is less than 5% of the population size for each sample. B. n1p11−p1≥10 and n2p21−p2≥10 C. The samples are dependent. D. The sample size is more than 5% of the population size for each sample. E. The samples are independent. F. The data come…The May 10, 2007 issue of The New England Journal of Medicine describes two large randomized, placebo-controlled trials of a vaccine for HPV-related cancer. HPV is human papillomavirus, the most common form of sexually transmitted infection. For the group of people who received the vaccine, the HPV-related cancer rate was much lower than for those who received a placebo. Which best describes the goal of this study?In randomized, double-blind clinical trials of a new vaccine, rats were randomly divided into two groups. Subjects in group 1 received the new vaccine while subjects in group 2 received a control vaccine. After the second dose, 111 of 670 subjects in the experimental group (group 1) experienced drowsiness as a side effect. After the second dose, 68 of 551 of the subjects in the control group (group 2) experienced drowsiness as a side effect. Does the evidence suggest that a higher proportion of subjects in group 1 experienced drowsiness as a side effect than subjects in group 2 at the α=0.05 level of significance? a. Find the test statistic for this hypothesis test. Round to two decimal places as needed.
- The Physicians' Health Study was a randomized clinical trial, one goal of which was to assess the effect of aspirin in preventing myocardial infarction (MI). Participants were 22,000 male physicians ages 40-84 and free of cardiovascular disease in 1982. The physicians were randomized to either active aspirin (one white pill containing 325 mg of aspirin taken every other day) or aspirin placebo (one white placebo pill taken every other day). Suppose we assume that the incidence of MI is 0.005 per year among participants who actually take placebo and that aspirin prevents 20% of MIs. How many participants need to be enrolled in each group to have an **80%** chance of detecting a significant difference using a **one-sided test** with $\alpha=0.05$ if **compliance is perfect**?Noting the paucity of information on the effect of estrogen on platelet membrane fatty acid composition, Ranganath et al. (A-48) conducted a study to examine the possibility that changes may be present in postmenopausal women and that these may be reversible with estrogen treatment. The 31 women recruited for the study had not menstruated for at least 3 months or had symptoms of the menopause. No woman was on any form of hormone replacement therapy (HRT) at the time she was recruited. Table 5 shows the platelet membrane linoleic acid values before and after a period of HRT. Does the data follow normal distribution?Noting the paucity of information on the effect of estrogen on platelet membrane fatty acid composition, Ranganath et al. (A-48) conducted a study to examine the possibility that changes may be present in postmenopausal women and that these may be reversible with estrogen treatment. The 31 women recruited for the study had not menstruated for at least 3 months or had symptoms of the menopause. No woman was on any form of hormone replacement therapy (HRT) at the time she was recruited. Table 5 shows the platelet membrane linoleic acid values before and after a period of HRT. Is HRT significantly effective?
- Noting the paucity of information on the effect of estrogen on platelet membrane fatty acid composition, Ranganath et al. (A-48) conducted a study to examine the possibility that changes may be present in postmenopausal women and that these may be reversible with estrogen treatment. The 31 women recruited for the study had not menstruated for at least 3 months or had symptoms of the menopause. No woman was on any form of hormone replacement therapy (HRT) at the time she was recruited. Table 5 shows the platelet membrane linoleic acid values before and after a period of HRT. Are the two variances equal?Noting the paucity of information on the effect of estrogen on platelet membrane fatty acid composition, Ranganath et al. (A-48) conducted a study to examine the possibility that changes may be present in postmenopausal women and that these may be reversible with estrogen treatment. The 31 women recruited for the study had not menstruated for at least 3 months or had symptoms of the menopause. No woman was on any form of hormone replacement therapy (HRT) at the time she was recruited. Table 5 shows the platelet membrane linoleic acid values before and after a period of HRT. What is the lower limit of CI? 4 decimal placesHistorically, the proportion of people who trade in their old car to a car dealer when purchasing a new car is 48%. Over the previous six months, in a sample of 115 new car buyers, 46 have traded in their old car. To determine (at the 10% level of significance) whether the proportion of new car buyers that trade in their old car has this is  statistically significantly decreased, what can you conclude concerning the null hypothesis? A) reject the null hypothesis Or B) fail to reject the null hypothesis