A student needs to analyze a mixture containing an alcohol and a ketone by silica gel TLC. After consulting Table 18.1, suggest a likely developing solvent. TABLE 18.1 Relative polarities of common TLC solvents and organic compounds Common developing solvents Organic compounds by functional group class Alkanes, cycloalkanes Alkanes Toluene Alkenes Aromatic hydrocarbons Ethers, halocarbons Dichloromethane Diethyl ether Ethyl acetate Acetone (anhydrous) Ethanol (anhydrous) Methanol Acetonitrile Water Increasing polarity nydes, ketones, esters Amines Alcohols Carboxylic acids

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A student needs to analyze a mixture containing an alcohol
and a ketone by silica gel TLC. After consulting Table 18.1,
suggest a likely developing solvent.
TABLE 18.1 Relative polarities of common TLC solvents and organic compounds
Common developing solvents
Increasing polarity Organic compounds by functional group class
Alkanes, cycloalkanes
Alkanes
Toluene
Alkenes
Aromatic hydrocarbons
Ethers, halocarbons
Dichloromethane
Diethyl ether
Ethyl acetate
Acetone (anhydrous)
Ethanol (anhydrous)
Methanol
Acetonitrile
Water
nydes, ketones, esters
Amines
Alcohols
Carboxylic acids
Transcribed Image Text:A student needs to analyze a mixture containing an alcohol and a ketone by silica gel TLC. After consulting Table 18.1, suggest a likely developing solvent. TABLE 18.1 Relative polarities of common TLC solvents and organic compounds Common developing solvents Increasing polarity Organic compounds by functional group class Alkanes, cycloalkanes Alkanes Toluene Alkenes Aromatic hydrocarbons Ethers, halocarbons Dichloromethane Diethyl ether Ethyl acetate Acetone (anhydrous) Ethanol (anhydrous) Methanol Acetonitrile Water nydes, ketones, esters Amines Alcohols Carboxylic acids
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