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(a) What do initiation of the urea cycle and initiation of gluconeogenesis have in common? (b) produced, where does it take place, how is it allosterically regulated, and how is the allosteric regulator produced? What is the first committed step of the urea cycle, what reactants are used, what product is

(a) What do initiation of the urea cycle and initiation of gluconeogenesis have in common? (b) produced, where does it take place, how is it allosterically regulated, and how is the allosteric regulator produced? What is the first committed step of the urea cycle, what reactants are used, what product is

Biology: The Dynamic Science (MindTap Course List)
Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Chapter4: Cells
Section: Chapter Questions
Problem 11TYK
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4. The urea cycle was the first metabolic cycle to be discovered, predating the description of the citric acid cycle by 5 years. Hans Krebs along with Kurt Henseleit used their Warburg manometer (pictured) to monitor the use of carbon dioxide and ammonia in the synthesis of urea. In the presence of a slice of liver, urea could be produced, but the reaction require ornithine and citrulline. Since citrulline is not consumed during the course of the enzymatic cycle, but is rather regenerated, Krebs described 2N citrulline as a "catalyst" of the process. ОН ÑH2 (a) What do initiation of the urea cycle and initiation of gluconeogenesis have in common? What is the first committed step of the urea cycle, what reactants are used, what product is (b) produced, where does it take place, how is it allosterically regulated, and how is the allosteric regulator produced?
Transcribed Image Text:4. The urea cycle was the first metabolic cycle to be discovered, predating the description of the citric acid cycle by 5 years. Hans Krebs along with Kurt Henseleit used their Warburg manometer (pictured) to monitor the use of carbon dioxide and ammonia in the synthesis of urea. In the presence of a slice of liver, urea could be produced, but the reaction require ornithine and citrulline. Since citrulline is not consumed during the course of the enzymatic cycle, but is rather regenerated, Krebs described 2N citrulline as a "catalyst" of the process. ОН ÑH2 (a) What do initiation of the urea cycle and initiation of gluconeogenesis have in common? What is the first committed step of the urea cycle, what reactants are used, what product is (b) produced, where does it take place, how is it allosterically regulated, and how is the allosteric regulator produced?
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