(a) Which allele/s will MOST likely result in an anomalous phenotype? (b) Explain your answer in (a). (c) Which allele/s will LEAST likely result in an anomalous phenotype?

Human Anatomy & Physiology (11th Edition)
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Chapter1: The Human Body: An Orientation
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(a) Which allele/s will MOST likely result in an anomalous phenotype?

(b) Explain your answer in (a).

(c) Which allele/s will LEAST likely result in an anomalous phenotype?

(d) One of the alleles code for a protein that tend to clump together. Which allele is it? (Hint: Recall what you learned from protein/amino acid structure.)

Shown in the table are partial sequences (coding strand) of the normal human hemoglobin and
three variants that occur commonly in the human population. Some of these variants function as
normal hemoglobin, however, some negatively affect hemoglobin function.
Type of Hemoglobin
Base Position
7 10 13
16.25... 118 121 124 127
CTG ACC CCC GAG AGC AAC AGA TTC GAG
Normal hemoglobin
Allele Variant 1
Allele Variant 2
Allele Variant 3
CTG ACC CCC GTG AGC AAC AGA TTC GAG
CTG ACC CCC GAG AGC AAC AGA TCC GAG
CTG ACC CCC GAG ACC AAC AGA TTC GAG
(a) Which allele/s will MOST likely result in an anomalous phenotype?
Answer: [Select]
(b) Explain your answer in (a).
Explanation: [Select]
(c) Which allele/s will LEAST likely result in an anomalous phenotype?
Answer: [Select]
(d) One of the alleles code for a protein that tend to clump together. Which allele is it? (Hint: Recall
what you learned from protein/amino acid structure.)
Answer: [Select]
Transcribed Image Text:Shown in the table are partial sequences (coding strand) of the normal human hemoglobin and three variants that occur commonly in the human population. Some of these variants function as normal hemoglobin, however, some negatively affect hemoglobin function. Type of Hemoglobin Base Position 7 10 13 16.25... 118 121 124 127 CTG ACC CCC GAG AGC AAC AGA TTC GAG Normal hemoglobin Allele Variant 1 Allele Variant 2 Allele Variant 3 CTG ACC CCC GTG AGC AAC AGA TTC GAG CTG ACC CCC GAG AGC AAC AGA TCC GAG CTG ACC CCC GAG ACC AAC AGA TTC GAG (a) Which allele/s will MOST likely result in an anomalous phenotype? Answer: [Select] (b) Explain your answer in (a). Explanation: [Select] (c) Which allele/s will LEAST likely result in an anomalous phenotype? Answer: [Select] (d) One of the alleles code for a protein that tend to clump together. Which allele is it? (Hint: Recall what you learned from protein/amino acid structure.) Answer: [Select]
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