Answered: A. Circle the distal Histidine residue.…

A. Circle the distal Histidine residue. B. What is the function of the distal Histidine residue? C. What keeps bound oxygen “bent", and not binding orthogonal to the plane of the porphyrin?

Biology: The Dynamic Science (MindTap Course List)

4th Edition

ISBN:9781305389892

Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Chapter46: Gas Exchange: The Respiratory System

Section: Chapter Questions

Problem 12TYK

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Question

Please answer all questions

10) Consider the Fe(Il) heme center in hemoglobin. Iron is colored orange and dioxygen is colored red.
A. Circle the distal Histidine residue.
B. What is the function of the distal Histidine residue?
C. What keeps bound oxygen “bent", and not binding orthogonal to the plane of the porphyrin?
D. What would happen to Fe(lI) if oxygen were to bind perpendicular (orthogonal) to the plane of
the porphyrin?
E. What happens to the structure of the porphyrin when oxygen dissociates from hemoglobin?

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