All of the following are characteristics of defensins except: A. There are two classes of defensins B. They require high ionic strength to become active C. They have low variability and are highly conserved D. They have broad antimicrobial properties E. They lead to ionic burst
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All of the following are characteristics of defensins except:
A. There are two classes of defensins
B. They require high ionic strength to become active
C. They have low variability and are highly conserved
D. They have broad antimicrobial properties
E. They lead to ionic burst
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- Valinomycin is an ionophore antibiotic that renders biological membranes permeable to K+. Its side effects in patients with bacterial infections include a rise in body temperature and sweating. Explain.When two antimicrobial drugs are used at the same time, antagonistic effects can occur. Which of the following is NOT a possible antagonistic effect of combining two antimicrobial drugs? Increased elimination of one drug Increased activity of both drugs Increased toxicity Decreased therapeutic levels Decreased activity of both drugsgive correct option. Polyisocyanates are involved in the induction of the full spectrum of hypersensitivity responses and nonimmune inflammatory reactions including asthma. Which of the following statement is not correct with respect to these observations and impact on immunity? a. A person once sensitized to polyisocyanate can demonstrate group reactivity to this set of compounds. b. Individuals having an acute exposure to toluene diisocyanate is more likely to develop hypersensitivity then individuals chronically exposed to low vapor levels. c. A mechanism for this hypersensitivity is the toluene diisocyanate forms a covalent bond with proteins that are part of the airway resulting in the immune system developing a response to “self” proteins. d. Adaptive immunity can interact or “message” the Innate immune system to up or down regulate its expression. e. All of the statements are correct.
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- Why is it important to measure the pharmacokinetics(PK) and metabolism of an antibody drugThe anticlotting property of heparin is partly the result of the negative charges it carries. ( Q.) Which type of heparin is a better anticoagulant, one with a high or a low degree of polymerization?Prostaglandin is involved in all of the following EXCEPT: I.Relaxing and contracting smooth muscle II.Platelet aggregation III.hypersensitivity responses IV.Raising body temperature A. II & III only B. III only C. I only D. I & IV only