An autosomal recessive disease affects /200 dogs and the populadion is in Hardy-wenborg. a) what proporton of the poularon are cauners for the diseOse? b) A carrrer dog and an unknown dog are randomy saected from the popucaion and thoy have one offiring what is the foosibility the offspring is a carrier for tme disease?
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- In Table 2-1, state the recessive phenotype in each of theseven cases.. Consider the genotypes of two lines of chickens: thepure-line mottled Honduran is i/i ; D/D ; M/M ; W/W, andthe pure-line leghorn is I/I ; d/d ; m/m ; w/w, whereI = white feathers, i = colored feathersD = duplex comb, d = simplex combM = bearded, m = beardlessW = white skin, w = yellow skinThese four genes assort independently. Starting withthese two pure lines, what is the fastest and mostconvenient way of generating a pure line that has coloredfeathers, has a simplex comb, is beardless, and has yellowskin? Make sure that you showa. the breeding pedigree.b. the genotype of each animal represented.c. how many eggs to hatch in each cross, and why thisnumber.d. why your scheme is the fastest and the mostconvenientIf you knew that a devastating late-onset inherited disease runsin your family (in other words, a disease that does not appearuntil later in life) and you could be tested for it at the age of 20,would you want to know whether you are a carrier? Would youranswer be likely to change when you reach age 40?
- Neurospora of genotype a + c are crossed withNeurospora of genotype + b +. (Here, + is shorthandfor the wild-type allele.) The following tetrads areobtained (note that the genotype of the four sporepairs in an ascus are listed, rather than listing alleight spores):a + c a b c + + c + b c a b + a + ca + c a b c a + c a b c a b + a b c+ b + + + + + b + + + + + + c + + ++ b + + + + a b + a + + + + c + b +137 141 26 25 2 3a. In how many cells has meiosis occurred to yieldthese data?b. Give the best genetic map to explain these results.Indicate all relevant genetic distances, both betweengenes and between each gene and the centromere.c. Diagram a meiosis that could give rise to oneof the three tetrads in the class at the far right inthe listIn Figure 6-21, propose a specific genetic explanationfor individual Q (give a possible genotype, defining theallelesA prospective groom, who is unaffected, has a sisterwith cystic fibrosis (CF), an autosomal recessive disease.Their parents are unaffected. The brother plans to marrya woman who has no history of CF in her family. Whatis the probability that they will produce a CF child? Theyare both Caucasian, and the overall frequency of CF inthe Caucasian population is 1/2500—that is, 1 affectedchild per 2500. (Assume the population meets the Hardy–Weinberg assumptions.)
- The genotype XXY corresponds to: a. Klinefelter syndrome b. Turner syndrome c. Tripto-X d. Jacob syndromeMarcia saw an ad on television for ancestry DNA testingand thought, ”Why not?” She ordered a kit, swabbedher inner cheek, and returned the kit for analysis. Severalweeks later, she was surprised to learn that she was 17 percentNative American. An elderly great aunt confirmed that her mother’s family intermarried with members of Native American tribes in the Pacific Northwest in the early twentieth century. To investigate her maternal heritage, Marcia ordered a mitochondrial DNA (mtDNA) test, which confirmed her Native American ancestry. Based on these genetic results, she applied to several Native American tribes for enrollment as a tribal member. She was shocked when she was turned down. In discussions, tribal officials told her that DNA alone is not sufficient to define who is Native American. Tribal standards for enrollment vary, but usually cultural attributes such as knowledge of the language, customs, and history of the tribe are important considerations for enrollment decisions.…The mode of inheritance for this disease is recessive ?
- A man of blood group B is being sued by a woman of blood group A for paternity. The womans child is blood group O.a) If this man is actually the father of this child, specify the genotypes of both parents?b) If it was impossible for this group B man to be the father of a type O child, specify his genotype?c) If a man was blood group AB, could he be the father of group O child?Sickle cell anemia is an autosomal recessive genetic disorder. Because individuals affected bysickle cell anemia have defective hemoglobin proteins, their blood cannot transport oxygenproperly. There appears to be a relationship between the incidence of malaria and sickle cellanemia. Individuals with sickle cell anemia and carriers of the sickle cell allele have someresistance to malaria. Malaria is caused by the parasite Plasmodium and is transmitted among humans by mosquitoes. If scientists are successful in reducing significantly or eliminating malaria, the best predictionfor what will happen to the allele for sickle cell anemia in the population is that it willa. not be affected by the elimination of malariab. increase as its selective advantage is increasedc. be reduced as its selective advantage is decreasedd. disappear quickly as its selective advantage is increasedSickle cell anemia is an autosomal recessive genetic disorder. Because individuals affected bysickle cell anemia have defective hemoglobin proteins, their blood cannot transport oxygenproperly. There appears to be a relationship between the incidence of malaria and sickle cellanemia. Individuals with sickle cell anemia and carriers of the sickle cell allele have someresistance to malaria. Malaria is caused by the parasite Plasmodium and is transmitted amonghumans by mosquitoes.4. If scientists are successful in reducing significantly or eliminating malaria, the best predictionfor what will happen to the allele for sickle cell anemia in the population is that it willa. not be affected by the elimination of malariab. increase as its selective advantage is increasedc. be reduced as its selective advantage is decreasedd. disappear quickly as its selective advantage is increased