Antisense therapeutics are important because: Select one: a. They only act at the ribosome O b. They can be easily delivered to their sight of activity after systemic administration O c. They can be found in large quantities in the Golgi Od. They hybridise to the antisense strand of a DNA transcript They are being use as a routinely administered medicine O e. Ribozymes are good candidates as molecular therapeutics because Select one: O a. They are more stable than DNA is body fluids O b. They can easily cross biological barriers with out the aid of a drug delivery system Oc. They retain secondary structure that may point to an evolutionary link between RNA and protei Od. They are more stable than many proteins in body fluids Oe. They can be encoded into a plasmid and delivered as a DNA based construct give both answer only with little bit explanation Asap Thanks

Antisense therapeutics are important because: Select one: a. They only act at the ribosome O b. They can be easily delivered to their sight of activity after systemic administration O c. They can be found in large quantities in the Golgi Od. They hybridise to the antisense strand of a DNA transcript They are being use as a routinely administered medicine O e. Ribozymes are good candidates as molecular therapeutics because Select one: O a. They are more stable than DNA is body fluids O b. They can easily cross biological barriers with out the aid of a drug delivery system Oc. They retain secondary structure that may point to an evolutionary link between RNA and protei Od. They are more stable than many proteins in body fluids Oe. They can be encoded into a plasmid and delivered as a DNA based construct give both answer only with little bit explanation Asap Thanks

Biology: The Dynamic Science (MindTap Course List)

4th Edition

ISBN:9781305389892

Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Chapter18: Dna Technologies: Making And Using Genetically Altered Organisms, And Other Applications

Section: Chapter Questions

Problem 3TYK: Why are antibiotic resistance markers such as ampR important components of bacterial plasmid cloning...

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Which one of the following statements is true? a. Dideoxynucleotides signal the end of DNA replication in a cell b. None of the provided answers are true c. The DNA sequence determined by an autoradiogram should be identical to the template strand DNA sequence d. The probe hybridization solution used in the Sothern blot technique is approximately pH 10.0 e. The transfer buffer used in the Southern blot technique is approximately pH 7.0
P-element transformation is a method that can be used to generate transgenic ______. A.) mice B.) bacteria C.) fruit flies D.) plants
DNA molecular with complementary sticky ends associate by (a) covalent bonds (b) hydrogen bonds (c) ionic bonds (d) disulfide bonds (e) phosphodiester linkages
Why are antibiotic resistance markers such as ampR important components of bacterial plasmid cloning vectors? a. The plasmid must have resistance to accept DNA inserts. b. They allow the detection of plasmids that contain an inserted DNA fragment. c. They ensure the presence of the ori site. d. They ensure that the plasmid can be cut by a restriction enzyme. e. They allow identification of bacteria that have taken up a plasmid.
(a) Describe the actions with reason that should be taken under the following situations: (i) An unlabelled collection tube with a requisition for a V Leiden test is received in the laboratory. (ii) After PCR, the amplification control has failed to yield a product. (iii) DNA is stored overnight in a refrigerator set at 8oC but reads 14 oC. (iv) An isolated DNA sample is to be stored for at least 6 months. (v) The expiration date on a reagent has passed. (b) Explain briefly about genetic testing for new-born, including the importance of genetic testing and the disorder that genetic testing can detect.
Which one of the following statements about BamHI is incorrect? a. it can be used to digest DNA at very specific and predictable locations. b. Its natural role is for degradation of foreign DNA molecules c. The sequence recognized by BamHI is palindromic d. BamHI generates short overhangs of single stranded DNA e. It is isolated from the bacterial species E. coli
Write the advantages and disadvantages of applying such application in the DNA of an organism. a. Drug delivery systems that are based on bacterial or viral host. b. Producing genetically modified organisms to enhance food production. c. Combining two or more genes in one organism to enhance its traits. d. DNA manipulation of certain species to produce organs for harvesting.
Which statement is true? a. There is no danger involved in recombinant DNA research in humans. b. Stringent safety rules make the use of recombinant DNA research impossible. c. There is no danger in releasing recombinant organisms into the environment. d. Stringent safety rules make the use of recombinant DNA research possible. e. There is no danger involved in recombinant DNA research in bacteria.
Some scientists are trying to engineer bacteriophageto treat bacterial infections in humans when theinfections do not respond to chemical antibiotics.a. What possible advantages might phage therapyhave over antibiotic therapy?b. Describe potential difficulties that would need tobe overcome for phage therapy to succeed.c. How might researchers best confront the issue thatbacterial cells could become resistant to bacteriophage just as they could to antibiotics?
Probes for cloned genes use ____. a. certain bacteria that glow when they take up the genes b. specific antibodies that kill all the cells c. complementary nucleotide sequences tagged with a detectable label d. specific enzymes that lyse all the cells e. DNA ligase
A biologist develops a new drug that seems to dramatically slow the onset of symptoms resulting from HIV infection. Close monitoring of HIV-infected cells reveals that the viral proteins are in the form of long polyproteins. What kind of drug did the biologist develop? A. It is a glycosyl transferase inhibitor. B. It is an integrase inhibitor C. It is a protease inhibitor. D. It is a CD4 inhibitor. please explain why which answer is correct and which is wrong and why
11 Enzyme assay A) Always involves asking a substrate B) Can be very smoke or very complex C) Always involves ultraviolet light D) A-C are incorrect 12 Isolation of chromosomal (total) DNA using a spin column A) Involves a filtration step to remove many different molecules B) Lysis is an optional step C) Elution is not necessary D) Results in a very pure protein preparation 13 Isolation of chromosomal (total) DNA using a spin column A) Cells must be used using an appropriate method B) Cell lysis is required C) Elution of DNA required regardless of the cell type used in the experiment D) A-C are correct. 14 Isolation of chromosomal (total) DNA using a spin column A) Washing the spin column is optional B) DNA must be eluted from the spin column C) Does not involve centrifugation D) Only molecules that are supposed to bind to the column do so.