Application # 3 People with diabetes often sustain vascular damage to their retina (a part of the eye). Levels of vascular endothelial growth factor (VEGF) are often used as a marker of the severity of retinal damage. In a study published in the New England Journal of Medicine, researchers performed an experimental laser treatment on seven diabetic patients in the hopes of reducing the rate of retinal damage. They measured VEGF levels prior to treatment and then three weeks after and found that VEGF decreased by an average of 4.2 ng/ml with a sample standard deviation of 2.85 ng/ml. Across the seven subjects, the distribution of paired differences was symmetric with no outliers. Part C: Using the T or Z value you found in Part B, report the two-sided p-value. Please report your answer to three decimal places (ie: 0.XXX)

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Author:David Poole
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Section4.6: Applications And The Perron-frobenius Theorem
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Application #3
People with diabetes often sustain vascular damage to their retina (a part of the eye).
Levels of vascular endothelial growth factor (VEGF) are often used as a marker of the
severity of retinal damage.
In a study published in the New England Journal of Medicine, researchers performed an
experimental laser treatment on seven diabetic patients in the hopes of reducing the rate
of retinal damage. They measured VEGF levels prior to treatment and then three weeks
after and found that VEGF decreased by an average of 4.2 ng/ml with a sample standard
deviation of 2.85 ng/ml. Across the seven subjects, the distribution of paired differences
was symmetric with no outliers.
Part C:
Using the T or Z value you found in Part B, report the two-sided p-value.
Please report your answer to three decimal places (ie: 0.XXX)
Transcribed Image Text:Application #3 People with diabetes often sustain vascular damage to their retina (a part of the eye). Levels of vascular endothelial growth factor (VEGF) are often used as a marker of the severity of retinal damage. In a study published in the New England Journal of Medicine, researchers performed an experimental laser treatment on seven diabetic patients in the hopes of reducing the rate of retinal damage. They measured VEGF levels prior to treatment and then three weeks after and found that VEGF decreased by an average of 4.2 ng/ml with a sample standard deviation of 2.85 ng/ml. Across the seven subjects, the distribution of paired differences was symmetric with no outliers. Part C: Using the T or Z value you found in Part B, report the two-sided p-value. Please report your answer to three decimal places (ie: 0.XXX)
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