bone marrow hematopoietic stem cells S. Intercept secreted by Th2 to activate 8 cell proliferation secreted on exposure to allergen, e.g. pollen is also an endogenous pyrogen, Le, stimulates hypothalamus to increase body temperature secreted by Tc to "kill" target cells secreted by Th to activate Th1 response (CMI) 1. 2. 3. 4. 5. IL-1 IL-2 Cytotoxin/porin Histamine IL-S

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