Briefly outline how the Philadelphia chromosome leads to chronic myelogenous leukemia.

Q: Putting everything together, explain how the sickle cell anemia character is maintained at…

A: Introduction Sickle cell anaemia is one of several inherited disorders known collectively as sickle…

Q: Using hemophilia as an example, discuss how mutations, genetics, and history interact in real-life…

A: Hemophilia It is a common hereditary coagulation blood disorder due to the deficiency or reduced…

Q: how  Misguided translocations can help cause Burkitt lymphoma?

A: Burkitt lymphoma is a rare cancer of the B-lymphocytes. It is a solid tumor that mostly affects…

Q: 2.2. Describe what are missense mutations and its effects on structure and function using…

A: Mutation is the basic cause of evolution. Mutation can be defined as any change in the chromosome or…

Q: explain in detail why the following risk factors may promote the pathogenesis of breast cancer Risk…

A: Introduction:  Breast cancer is a type of cancer that starts in the breast tissue. A lump in the…

Q: What are genetic screens?

A: Genetic screen is screen used in a genetic experiment to detect a mutant organism.

Q: why EGFR play a role in CRC and other cancer?

A: EGFR : It is epidermis growth factor receptor.  CRC:  Colorectal cancer. EGFR : It is one of the…

Q: Explain why the gene for sickle cell anemia may be beneficial to humans at some point. Describe…

A: Sickle cell anemia is an autosomal disease in which the red blood cells become sickle-shaped. In…

Q: Explain why cell injury due to genetic causes are alarmingly increasing each year.?

A: Cell injury is damage in the cell that occurs due to some external and internal…

Q: The standard notation for describing the common mutation in the HBB gene that, when homozygous,…

A: Sickle cell anemia is an inherited disorder which affects the formation of hemoglobin and disrupts…

Q: Explain the genes responsible for complex diseases such as coronary artery disease ?

A: “Coronary artery disease (CAD)” is a complex disease that is considered the leading cause of death…

Q: what does a blood typing concept map look like with 10 words or phrases?

A: Humans are born with different types of alleles which code for the blood groups . The blood group of…

Q: Explain the connection between the founder and the G8-C marker.

A: In this example the original mutation that caused  the huntington allele occurred in a germline cell…

Q: Mention the causative agents of DNA lesions in the human body that can lead to cancer.

A: The causative agents are environmental agents that alter the structure of DNA and lead to harmful…

Q: In Cystic Fibrosis: How is the gene/chromosome affected? How is the cell, tissue, and body systems…

A: Cystic fibrosis is an innate sickness that influences the lungs and stomach related framework. The…

Q: /hich type of colorectal cancer is considered to be an autosomal dominant disorder haracterized with…

A: Colorectal cancer is any cancer that affects the colon and the rectum. It acts as a growth on the…

Q: Define a Point mutation and give an example. What is sickle cell anemia and what causes it. What…

A: Mutation refers to the phenomena in which the structure of a gene or DNA sequence changes, resulting…

Q: How would you relate the cancer cellular pathophysiology with genomic instability?

A: Introduction  Cancer is well known disease now a day. In US, 1 in 2 women and 1 in 3 men develops…

Q: Discuss two reasons why the therapeutic use ofembryonic stem cells can present a problem.

A: The embryonic stem cells are pluripotent cells that possess the ability to differentiate into any…

Q: Given that this mutated allele will cause disease and death in individuals, what would you predict…

A: Sickel cell anemia is an autosomal recessive genetic disorder that affects the shape of red blood…

Q: Chronic myelogenous leukemia (CML) is also particularly well-studied. Most people with CML have a…

A: Chronic myelogenous leukemia is an uncommon type of cancer of the bone marrow where the spongy…

Q: What characteristics of the pedigree suggest that pancreatic cancer in this family is inherited as…

A: Introduction  Pedigree Analysis: This is the new approach to study the inheritance pattern in the…

Q: 1. The location of hemophilia C- factor XI is 4q35, where exactly is it? Describe. 2. Referring to…

A: Chromosomes carry several genes and their exact location is called as loci. It is represented by…

Q: Define amplified

A: Amplified is a term used to expand something.

Q: Explain about dominant negative mutation ?

A: Mutation is any change in the DNA or RNA sequence which may or may not alter the normal functioning…

Q: Besides CFTR, what othe gene is associated with cystic fibrosis?

A: Introduction Cystic fibrosis:- It is an inherited disorder that causes severe damage to the…

Q: How epistasis causes unexpected inheritance pattern of ABO blood type?

A: Genetics is a branch of science that deals with the study of genes, heredity, and genetic variation…

Q: Define common variants

A: A common variant is a part of a hypothesis "Common diseases-common variant" that accounts for the…

Q: Explain in as much detail as possible how to distinguish a leukemoid reaction from a leukemia.

A: Both leukemia and leukamoid reaction shows increase in WBC count but there are differences between…

Q: How Mutations at the Huntington disease locusare caused?

A: Huntington disease is an inherited rare disease that progressively degenerates the nerve cells…

Q: Hemophilia , Beta Thalassemia , and Sickle Cell Disease what do all of these disorders have in…

A: A mutation is a change in the sequence of the DNA. Mutations can result from the following: DNA…

Q: Explain the factors that reactivate the dormant herpes simplex virus (2 pts)    How can a defect…

A: Herpes simplex virus (HSV) causes herpes. The two firms of HSV are HSV-1 (causes oral herpes with…

Q: What is a A germline mutation?

A: A germinal mutation or germline mutation as the word indicates itself it is a mutation in germline…

Q: Give at least three (3) dosage forms in which liberation is altered?

A: The process by which medicine enters the body and liberates the active substance that has been…

Q: Briefly explain the role of genetic testing and the following inherited gene mutations linked to…

A: Genetic testing is a type of medical test which is performe to know the defective gene or proteins…

Q: Explain maternal-effect mutations?

A: Mutation means sudden changes occur in DNA sequences. The mutation occurs randomly. It also occurs…

Q: Explain about Cri du Chat Syndrome in Humans  ?

A: The disease is caused when there is a deviation from the normal occurs. Diseases can be communicable…

Q: What are paraneoplastic syndromes?

A: Paraneoplastic syndromes are rare conditions that can occur when cancer cells produce substances…

Q: What are the treatments for sickle cell anemia disorder and what are the possible treatments…

A: Sickle cell anemia disorder is a type of genetic or inherited blood disorder that results in the…

Q: Describe the mutational event that produces the MYC oncogene in Burkitt’s lymphoma. Why does the…

A: Burkitt lymphoma is a type of non-Hodgkin lymphoma (NHL) that affects adults and children. NHL is…

Q: Outline Knudson’s two-hit hypothesis of retinoblastoma and describe how it helps to explain…

A: The statistical analysis is performed by the Knudson on the retinoblastoma disorder. In this retina,…

Q: Compare and contrast the molecular mechanisms leading to FX syndrome and to FSHMD.

A: Introduction :- A gene originally known as FMR1 gene by scientists and responsible for FXS is…