c) The signal recognition particle (SRP) plays an important role in bringing proteins to the ER. There are multiple regions in the SRP that can bind to different proteins involved in the ER localization pathway. Please list at least two essential binding partners of the SRP.

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter11: Genome Alterations: Mutation And Epigenetics
Section: Chapter Questions
Problem 10QP: If the coding region of a gene (the exons) contains 2,100 base pairs of DNA, would a missense...
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This has 3 parts, please answer and explain in depth
a)
You are studying ER localization in mammalian cells. You notice that when a mutation
is introduced to protein A, there are no proteins in the ER at all. What is a reasonable identity of
protein A?
b)
Alternatively, when a mutation is introduced to protein B, only one protein that was
supposed to be in the ER is now in the cytoplasm. please suggest a specific type of sequence
within protein B in which this mutation might have occurred.
Transcribed Image Text:a) You are studying ER localization in mammalian cells. You notice that when a mutation is introduced to protein A, there are no proteins in the ER at all. What is a reasonable identity of protein A? b) Alternatively, when a mutation is introduced to protein B, only one protein that was supposed to be in the ER is now in the cytoplasm. please suggest a specific type of sequence within protein B in which this mutation might have occurred.
c) The signal recognition particle (SRP) plays an important role in bringing proteins to the
ER. There are multiple regions in the SRP that can bind to different proteins involved in the ER
localization pathway. Please list at least two essential binding partners of the SRP.
Transcribed Image Text:c) The signal recognition particle (SRP) plays an important role in bringing proteins to the ER. There are multiple regions in the SRP that can bind to different proteins involved in the ER localization pathway. Please list at least two essential binding partners of the SRP.
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