Calculate the pH at which pilocarpine (basic drug) starts to precipitate from a 2% w/v aqueous solution of its hydrochloride salt. Given the following data: The solubility of pilocarpine in water=0.207 % w/v The pka of pilocarpine =6.61 The molecular weight of pilocarpine=208.3 g/l The molecular weight of pilocarpine hydrochloride = 244.8 g

Calculate the pH at which pilocarpine (basic drug) starts to precipitate from a 2% w/v aqueous solution of its hydrochloride salt. Given the following data: The solubility of pilocarpine in water=0.207 % w/v The pka of pilocarpine =6.61 The molecular weight of pilocarpine=208.3 g/l The molecular weight of pilocarpine hydrochloride = 244.8 g

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter15: Acid-base Equilibria

Section: Chapter Questions

Problem 20Q: Consider the following two acids: pKa1 = 2.98; pKa2 = 13.40 HO2CCH2CH2CH2CH2CO2H Adipic acid pKa1 =...

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