Can you show mechanism of an example of grignard reagent with epoxies and H3O+ and the various examples provided (powerful nucleophile/base)Grignard reagent is used in synthesis of various classes of organiccompounds:(some examples)1° alcoholR-CH₂CH₂OHRR-C-OHR0O epoxide9⁰⁰⁰(ii) H₂O*hydrocarbon/deuterated hydrocarbon(i) RCOOR(ii) H₂O*for these two rxns uséR-H/R-DH₂O/D₂O/ROH (1) COfin) H₂O+6- 8+(i) HC(O)HR—Mg▬X | (ii) H30*Grignard reagentcarboxylic acidR-COOHR-CH₂OHany other aldehyde 1° alcohol(ii) H₂O*R-CH-OH

Solution:- In Epoxides reaction with Grignard reagents to form alcohols The nucleophilic attack of…

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Can you show mechanism of an example of grignard reagent with epoxies and H3O+ and the various examples provided

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter19: Eas: Electrophilic Aromatic Substitution

Section: Chapter Questions

Problem 5E

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Concept explainers

Designing a Synthesis

Organic synthesis is a branch of chemical synthesis that involves the planned construction of organic compounds/molecules from smaller units that possess functional groups. Friedrich Wöhler was the first scientist who designed the synthesis of an organic compound, urea from inorganic starting materials silver cyanate with ammonium chloride via a simple, one-step synthesis.

Question

Can you show mechanism of an example of grignard reagent with epoxies and H3O+ and the various examples provided

(powerful nucleophile/base)
Grignard reagent is used in synthesis of various classes of organic
compounds:
(some examples)
1° alcohol
R-CH₂CH₂OH
R
R-C-OH
R
0
O epoxide
9⁰⁰⁰
(ii) H₂O*
hydrocarbon/deuterated hydrocarbon
(i) RCOOR
(ii) H₂O*
for these two rxns usé
R-H/R-D
H₂O/D₂O/ROH (1) CO
fin) H₂O+
6- 8+
(i) HC(O)H
R—Mg▬X | (ii) H30*
Grignard reagent
carboxylic acid
R-COOH
R-CH₂OH
any other aldehyde 1° alcohol
(ii) H₂O*
R-CH-OH

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