11. The SARS (SARS CoV-1) virus and Covid19 (SARS-CoV-2) virus both bind to the angiotensin-converting enzyme (ACE2) receptor, but with different affinities. The Spike protein of SARS has a Kd of 330NM and Covid19 has 15nM. a. On the same graph, draw a "conceptual" binding curve for both viruses' spike proteins and the ACE 2 receptor. Label the graph appropriately.) b. What is your interpretation of the graph in (a)a, c. The new variant of Covid19, first identified in England is up to 70% more infectious than Covid19. What would you anticipate is happening to the Kd for this new variant?

11. The SARS (SARS CoV-1) virus and Covid19 (SARS-CoV-2) virus both bind to the angiotensin-converting enzyme (ACE2) receptor, but with different affinities. The Spike protein of SARS has a Kd of 330NM and Covid19 has 15nM. a. On the same graph, draw a "conceptual" binding curve for both viruses' spike proteins and the ACE 2 receptor. Label the graph appropriately.) b. What is your interpretation of the graph in (a)a, c. The new variant of Covid19, first identified in England is up to 70% more infectious than Covid19. What would you anticipate is happening to the Kd for this new variant?

Biology: The Dynamic Science (MindTap Course List)

4th Edition

ISBN:9781305389892

Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Chapter21: Microevolution: Genetic Changes Within Populations

Section: Chapter Questions

Problem 11TYK

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