In order to optimize acetylcholinesterase inhibition, a set of benzylamine derivatives were studied, and the following relationship was found: log= = -0.187 n + 0.57o + 3.893 (a). Based on the expected change in the Hammett constant (o ), how would you expect the activity of compound B to compare to compound A? NC B
In order to optimize acetylcholinesterase inhibition, a set of benzylamine derivatives were studied, and the following relationship was found: log= = -0.187 n + 0.57o + 3.893 (a). Based on the expected change in the Hammett constant (o ), how would you expect the activity of compound B to compare to compound A? NC B
Chemistry for Today: General, Organic, and Biochemistry
9th Edition
ISBN:9781305960060
Author:Spencer L. Seager, Michael R. Slabaugh, Maren S. Hansen
Publisher:Spencer L. Seager, Michael R. Slabaugh, Maren S. Hansen
Chapter20: Enzymes
Section: Chapter Questions
Problem 20.75E: In the multienzyme sequence shown below, molecules of D are able to fit to the enzyme E1 and prevent...
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