Classify the inhibitor characteristics according to one of three types of inhibition: reversible competitive, reversible noncompetitive, or irreversible. Reversible competitive Reversible noncompetitive Irreversible Answer Bank inhibitor binds covalently and permanently at active site inhibitor binds noncovalently at site other than active site inhibitor does not alter the maximum reaction rate inhibitor structure resembles substrate structure

Classify the inhibitor characteristics according to one of three types of inhibition: reversible competitive, reversible noncompetitive, or irreversible. Reversible competitive Reversible noncompetitive Irreversible Answer Bank inhibitor binds covalently and permanently at active site inhibitor binds noncovalently at site other than active site inhibitor does not alter the maximum reaction rate inhibitor structure resembles substrate structure

Organic And Biological Chemistry

7th Edition

ISBN:9781305081079

Author:STOKER, H. Stephen (howard Stephen)

Publisher:STOKER, H. Stephen (howard Stephen)

Chapter10: Enzymes And Vitamins

Section: Chapter Questions

Problem 10.64EP: Indicate whether each of the following statements describes a reversible competitive inhibitor, a...

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Indicate whether each of the following statements describes a reversible competitive inhibitor, a reversible noncompetitive inhibitor, or an irreversible inhibitor. More than one answer may apply. a. It bonds covalently to the enzyme active site. b. The inhibitor effect can be reversed by the addition of more substrate. c. Inhibitor structure must be somewhat similar to that of the substrate. d. The inhibitor and substrate cannot bind to the enzyme simultaneously.
Based on the graphical information in Problem 21-41 about enzymes A and B indicate whether the enzyme activity of enzyme B increases or decreases when the following changes in reaction conditions are made. a. pH decreases from 7.6 to 7.2 b. pH increases from 7.2 to 7.4 c. temperature decreases from 37.8C to 37.6C d. temperature increases from 38.2C to 38.4C
Based on the graphical information in Problem 21-41 about enzymes A and B a. What is the optimum pH for enzyme B? b. What is the optimum temperature for enzyme A? c. Which enzyme has the greater activity at a pH of 7.2? d. Which enzyme has the greater activity at a temperature of 37.2C?
Indicate whether each of the following statements concerning different types of enzyme inhibitors is true or false. a. A reversible competitive inhibitor temporarily blocks an enzymes active site. b. A reversible noncompetitive inhibitor permanently changes the shape of an enzymes active site. c. An irreversible inhibitor temporarily changes the shape of an enzymes active site. d. Insecticides are examples of reversible noncompetitive inhibitors.
The human body has an average pH of about 7 and a temperature of about 37C. Use graphs to illustrate enzyme activity in the human body as a function of the following: a. Substrate concentration b. Enzyme concentration c. pH include pH optimum value d. Temperature include temperature optimum value
Draw a graph that shows the effect of increasing substrate concentration on the rate of an enzyme-catalyzed reaction (at constant temperature, pH, and enzyme concentration).